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2024

Associations between pathological features and risk of metachronous colorectal cancer

Authors Zhang Y, Win AK, Makalic E. et al., and Jenkins MA.
Citation Int J Cancer. 2024 Apr 27.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/38676439
PMCID In process
Improved risk stratification scheme for mismatch repair proficient stage II colorectal cancers using the digital pathology biomarker QuantCRC

Authors Wu C, Pai RK, Kosiorek H. et al., and Pai RK.
Citation Clin Cancer Res. 2024 Feb 29.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/38421684
PMCID PMC11062828
Genome-Wide Gene-Environment Interaction Analyses to Understand the Relationship between Red Meat and Processed Meat Intake and Colorectal Cancer Risk

Authors Stern MC, Sanchez Mendez J, Kim AE. et al., and Gauderman WJ.
Citation Cancer Epidemiol Biomarkers Prev. 2024 Mar 1;33(3):400-410.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/38112776
PMCID PMC10120801
Genotoxic colibactin mutational signature in colorectal cancer is associated with clinicopathological features, specific genomic alterations and better survival

Authors Georgeson P, Steinfelder RS, Harrison TA. et al., and Buchanan DD.
Citation medRxiv. 2024 Jan 30:2023.03.10.23287127.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/37090539
PMCID PMC10120801
Intratumoral presence of the genotoxic gut bacteria pks+ E. coli, Enterotoxigenic Bacteroides fragilis, and Fusobacterium nucleatum and their association with clinicopathological and molecular features of colorectal cancer

Authors Joo JE, Chu YL, Georgeson Pet al., and Buchanan DD
Citation Br J Cancer. 2024 Mar;130(5):728-740.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/38200234
PMCID PMC10912205
Epidemiologic factors in relation to colorectal cancer risk and survival by genotoxic colibactin mutational signature

Authors Thomas CE, Georgeson P, Qu C. et al., and Peters U, Phipps AI.
Citation Cancer Epidemiol Biomarkers Prev. 2024 Jan 22;.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/38252034
PMCID PMC10990777
The Mutographs biorepository: A unique genomic resource to study cancer around the world

Authors Perdomo S, Abedi-Ardekani B, de Carvalho AC. et al., and Brennan P.
Citation Cell Genom. 2024 Jan 31:100500.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/38325367
PMCID PMC10943582
Genome-wide association study and Mendelian randomization analyses provide insights into the causes of early-onset colorectal cancer

Authors Laskar RS, Qu C, Huyghe JR. et al., and Gunter, Peters, Murphy
Citation Ann Oncol. 2024 Feb 24:S0923-7534(24)00058-9.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/38408508
PMCID In process

2023

Molecular Characteristics of Early-onset Colorectal Cancer According to Detailed Anatomical Locations: Comparison to Later-onset Cases

Authors Ugai T, Haruki K, Harrison TA. et al., and Ogino S.
Citation Am J Gastroenterol. 2023 Apr 1;118(4):712-726.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/36707929
PMCID PMC10065351
Validation of a Genetic-Enhanced Risk Prediction Model for Colorectal Cancer in a Large Community-Based Cohort

Authors Su YR, Sakoda LC, Jeon J. et al., and Hsu L
Citation Cancer Epidemiol Biomarkers Prev. 2023 Mar 6; 32(3):353-362.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/36622766
PMCID PMC9992158
Elucidating the Risk of Colorectal Cancer for Variants in Hereditary Colorectal Cancer Genes

Authors Mahmood K, Thomas M, Qu C. et al., and Peters U.
Citation Gastroenterology. 2023 Oct;165(4):1070-1076.e3.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/37453563
PMCID PMC10866455
Using DEPendency of association on the number of Top Hits (DEPTH) as a complementary tool to identify novel colorectal cancer susceptibility loci

Authors Lai J, Wong CK, Schmidt D. et al., and Makalic E.
Citation Cancer Epidemiol Biomarkers Prev. 2023 Jun 26;EPI-22-1209.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/37364297
PMCID PMC10529807
A Highly Sensitive Pan-Cancer Test for Microsatellite Instability

Authors Bacher, JW, Edho EB, Strauss EE, et al., et al., and Halberg RB.
Citation J Mol Diagn. 2023 Aug 5;25(11):806-826.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/37544360
PMCID PMC10629437
The association between genetically elevated polyunsaturated fatty acids and risk of cancer

Authors Haycock PC, Borges MC, Burrows K, et al, and Martin RM.
Citation EBioMedicine. 2023 May;91:104510.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/37086649
PMCID PMC10148095
Probing the diabetes and colorectal cancer relationship using gene – environment interaction analyses

Authors Dimou N, Kim AE, Flanagan O, et al, and Peters U.
Citation Br J Cancer. 2023 Aug;129(3):511-520.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/37365285
PMCID PMC10403521
Identifying primary and secondary MLH1 epimutation carriers displaying low-level constitutional MLH1 methylation using droplet digital PCR and genome-wide DNA methylation profiling of colorectal cancers

Authors Joo JE, Mahmood K, Walker R, et al, and Buchanan DD.
Citation Clin Epigenetics. 2023 Jun 3;15(1):95.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/37270516
PMCID PMC10239107
Identifying metabolic features of colorectal cancer liability using Mendelian randomization

Authors Bull CJ, Hazelwood E, Bell JA, et al, and Vincent EE.
Citation medRxiv. 2023 Aug 1;2023.03.10.23287084.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/36945480
PMCID PMC10029059
Genome-wide interaction analysis of folate for colorectal cancer risk

Authors Bouras E, Kim AE, Lin Y, et al, and Tsilidis KK.
Citation Am J Clin Nutr. 2023 Aug 26;S0002-9165(23)66108-8.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/37640106
PMCID PMC10636229
Genetically proxied glucose-lowering drug target perturbation and risk of cancer: a Mendelian randomisation analysis

Authors Yarmolinsky J, Bouras E, Constantinescu A, et al, and Tsilidis KK.
Citation Diabetologia. 2023 Aug;66(8):1481-1500.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/37171501
PMCID PMC10317892
Genetically determined circulating resistin concentrations and risk of colorectal cancer: a two-sample Mendelian randomization study

Authors Pham TT, Nimptsch K, Papadimitriou N, et al, and Pischon T.
Citation J Cancer Res Clin Oncol. 2023 Aug 21.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/37599317
PMCID PMC10602946
Elucidating the Risk of Colorectal Cancer for Variants in Hereditary Colorectal Cancer Genes

Authors Mahmood K, Thomas M, Qu C, et al, and Peters U.
Citation Gastroenterology. 2023 Oct;165(4):1070-1076.e3.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/37453563
DNA Mismatch Repair Gene Variant Classification: Evaluating the Utility of Somatic Mutations and Mismatch Repair Deficient Colonic Crypts and Endometrial Glands

Authors Walker R, Mahmood K, Como J, et al, and Buchanan DD; ANGELS Study.
Citation Cancers (Basel). 2023 Oct; 15(20): 4925.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/37894291
PMCID PMC10605939
Combining Asian-European Genome-Wide Association Studies of Colorectal Cancer Improves Risk Prediction Across Race and Ethnicity

Authors Thomas M, Su YR, Rosenthal EA. et al., and Peters U, Hsu L.
Citation medRxiv. 2023 Jan 19:2023.01.19.23284737.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/36789420
PMCID PMC9928144
A genetic locus within the FMN1/GREM1 gene region interacts with body mass index in colorectal cancer risk

Authors Aglago EK, Kim AE, Lin Y, et al, and Campbell PT.
Citation Cancer Res. 2023 May 30;CAN-22-3713.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/37249599
PMCID PMC10391330
DNA Methylation Profile in CpG-depleted Regions Uncovers a High-Risk Subtype of Early-stage Colorectal Cancer

Authors Yu H, Wang X, Bai L, Tang G. et al
Citation J Natl Cancer Inst. 2023 Jan 10;115(1):52-61.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/36171645/
PMCID PMC10089593
T cell-inflamed gene expression profile is associated with favorable disease-specific survival in non-hypermutated microsatellite-stable colorectal cancer patients

Authors Yin G, Harrison TA, Thomas SS. et al
Citation Cancer Med. 2023 Mar;12(6):6583-6593.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/36341526/
PMCID PMC10067089
A tumor focused approach to resolving the etiology of DNA mismatch repair deficient tumors classified as suspected Lynch syndrome

Authors Walker R, Mahmood K, Joo JE. et al
Citation J Transl Med. 2023 Apr 26;21(1):282.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/37101184/
PMCID PMC10134620
A tumor focused approach to resolving the etiology of DNA mismatch repair deficient tumors classified as suspected Lynch syndrome

Authors Walker R, Mahmood K, Joo JE. et al
Citation medRxiv. 2023 Mar 1;2023.02.27.23285541.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/36909643/
PMCID PMC10002795
Evaluating Multiple Next-Generation Sequencing–Derived Tumor Features to Accurately Predict DNA Mismatch Repair Status

Authors Walker R, Georgeson P, Mahmood K. et al
Citation J Mol Diagn. 2023 Feb;25(2):94-109.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/36396080/
PMCID PMC10424255
Prognostic role of detailed colorectal location and tumor molecular features: analyses of 13,101 colorectal cancer patients including 2994 early-onset cases

Authors Ugai T, Akimoto N, Haruki K. et al
Citation J. Gastroenterol. 2023 Mar;58(3):229-245.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/36648535/
PMCID PMC10203916
Separating the effects of early and later life adiposity on colorectal cancer risk: a Mendelian randomization study

Authors Papadimitriou N, Bull CJ, Jenab M. et al
Citation BMC Med. 2023 Jan 4;21(1):5.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/36600297/
PMCID PMC9814460
Body Mass Index and Molecular Subtypes of Colorectal Cancer

Authors Murphy N, Newton CC, Song M. et al
Citation J Natl Cancer Inst. 2023 Feb 8;115(2):165-173.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/36445035/
PMCID PMC9905970
Genetic Predictors for Fecal Propionate and Butyrate-Producing Microbiome Pathway Are Not Associated with Colorectal Cancer Risk: A Mendelian Randomization Analysis

Authors Lu Y, Zhao YC, Chang-Claude J. et al
Citation Cancer Epidemiol Biomarkers Prev. 2023 Feb 6;32(2):281-w86.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/36512731/
PMCID PMC9905300
Genome-Wide Analyses Characterize Shared Heritability Among Cancers and Identify Novel Cancer Susceptibility Regions

Authors Lindström S, Wang L, Feng H. et al
Citation J Natl Cancer Inst. 2023 Jun 8;115(6):712-732.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/36929942/
PMCID PMC10248849
Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

Authors Fernandez-Rozadilla C, Timofeeva M, Chen Z. et al
Citation Nat Genet. 2023 Jan;55(1):89-99.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/36539618/
PMCID PMC10094749
Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

Authors Fernandez-Rozadilla C, Timofeeva M, Chen Z. et al
Citation Nat Genet. 2023 Mar;55(3):519-520.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/36782065/
PMCID Erratum
Genome-wide interaction study with smoking for colorectal cancer risk identifies novel genetic loci related to tumor suppression, inflammation and immune response

Authors Carreras-Torres R, Kim AE, Lin Y. et al
Citation Cancer Epidemiol Biomarkers Prev. 2023 Mar 6;32(3):315-328.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/36576985/
PMCID PMC9992283

2022

Molecular Characteristics of Early-onset Colorectal Cancer According to Detailed Anatomical Locations: Comparison to Later-onset Cases

Authors Ugai T, Haruki K, Harrison TA. et al
Citation Am J Gastroenterol. 2023 Apr 1;118(4):712-726.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/36707929/
PMCID PMC10065351
Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium

Authors Møller P, Seppälä T, Dowty JG. et al
Citation Hered Cancer Clin Pract. 2022 Oct 1;20(1):36.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/36182917/
PMCID PMC9526951
Beyond GWAS of Colorectal Cancer: Evidence of Interaction with Alcohol Consumption and Putative Causal Variant for the 10q24.2 Region

Authors Jordahl KM, Shcherbina A, Kim AE. et al
Citation Cancer Epidemiol Biomarkers Prev. 2022 May 4;31(5):1077-1089.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/35438744/
PMCID PMC9081195
Interactions between folate intake and genetic predictors of expression associated with colorectal cancer risk

Authors Haas CB, Su YR, Petersen P. et al
Citation Sci Rep. 2022 Nov 7;12(1):18852.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/36344807/
PMCID PMC9640550
Genetic regulation of DNA methylation yields novel discoveries in GWAS of colorectal cancer

Authors Barfield R, Huyghe JR, Lemire M. et al
Citation Cancer Epidemiol Biomarkers Prev. 2022 May 4;31(5):1068-1076.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/35247911/
PMCID PMC9081265
Body Mass Index, sex, non-steroidal anti-inflammatory drug medications, smoking and alcohol are differentially associated with World Health Organisation criteria and colorectal cancer risk in people with Serrated Polyposis Syndrome: an Australian case-control study

Authors Anthony E, Reece JC, Milanzi E. et al
Citation BMC Gastroenterol. 2022 Nov 26;22: 489.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/36435745/
PMCID PMC9701413
Associations Between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis

Authors Murphy N, Song M, Papadimitriou N. et al
Citation JNCI. 2022 May 9; 114(5): 740-752.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/35048991/
PMCID PMC9086764
Genetically-proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers

Authors Yarmolinsky J, Díez-Obrero V, Richardson TG. et al
Citation Plos Medicine. 2022 Feb; 19(2): e1003897.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/35113855/
PMCID PMC8812899
Association of germline TYK2 variation with lung cancer and non-Hodgkin lymphoma risk

Authors Yarmolinsky J, Amos CI, Hung RJ. et al
Citation Int J Cancer. 2022 Dec 15;151(12):2155-2160.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/35747941/
PMCID PMC9588593
Genome-Wide Interaction Analysis of Genetic Variants with Menopausal Hormone Therapy for Colorectal Cancer Risk

Authors Tian Y, Kim AE, Bien SA. et al
Citation J Natl Cancer Inst. 2022 Aug 8;114(8):1135-1148.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/35512400/
PMCID PMC9360460
Large-scale integrated analysis of genetics and metabolomic data reveals potential links between lipids and colorectal cancer risk

Authors Shu X, Chen Z, Long J, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2022 Mar 10; cebp.EPI-21-1008-E.2021.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/35266989/
PMCID PMC9354799
Germline MBD4 deficiency causes a multi-tumor predisposition syndrome

Authors Palles C, West HD, Chew E, et al.
Citation Am J Hum Genet. 2022 May 5;109(5):953-960.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/35460607/
PMCID PMC9118112
Quantitative pathologic analysis of digitized images of colorectal carcinoma improves prediction of recurrence free survival

Authors Pai RK, Banerjee I, Shivji S. et al
Citation Gastroenterology. 2022 Aug 16;S0016-5085(22)00951-9.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/35985511/
PMCID PMC9716432
A validation of models for prediction of mismatch repair gene mutations

Authors Shyr C, Blackford AL, Huang T. et al
Citation Genet Med. 2022 Oct;24(10):2155-2166.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/35997715/
PMCID NIHMID: 1910759
Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation

Authors Martin S, Tyrrell J, Thomas EL. et al
Citation Elife. 2022 Jan 25;11:e72452.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/35074047/
PMCID PMC8789289
Genome-wide association study identifies tumor anatomical site-specific risk variants for colorectal cancer survival

Authors Labadie JD, Savas S, Harrison TA. et al
Citation Sci Rep. 2022 Jan 7;12(1):127.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/34996992/
PMCID PMC8741984
Beyond GWAS of Colorectal Cancer: Evidence of Interaction with Alcohol Consumption and Putative Causal Variant for the 10q24.2 Region

Authors Jordahl KM, Shcherbina A, Kim AE, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2022 May 4;31(5):1077-1089.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/35438744/
PMCID PMC9081195
Diabetes mellitus in relation to colorectal tumor molecular subtypes: A pooled analysis of more than 9000 cases

Authors Harlid S, Van Guelpen B, Qu C. et al
Citation Int J Cancer. 2022 Aug 1;151(3):348-360.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/35383926/
PMCID PMC9251811
Identifying colorectal cancer caused by biallelic MUTYH pathogenic variants using tumor mutational signatures

Authors Georgeson P, Harrison TA, Pope BJ. et al
Citation Nat Commun. 2022 Jun 6;13(1):3254.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/35668106/
PMCID PMC9170691
Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals

Authors Chen H, Majumdar A, Wang L, et al.
Citation HGG Adv. 2021 Jul 8;2(3):100041.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/34355204/
PMCID PMC8336922
Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study

Authors Berstein FM, McCartney DL, Lu AT. et al
Citation eLife. 2022 Mar 29;11:e75374.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/35346416/
PMCID PMC9049976
Genetic regulation of DNA methylation yields novel discoveries in GWAS of colorectal cancer

Authors Barfield R, Huyghe JR, Lemire M, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2022 Mar3;cebp.0724.2021.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/35247911/
PMCID PMC9081265
Association between germline variants and somatic mutations in colorectal cancer

Authors Barfield R, Qu C, Steinfelder RS. et al
Citation Sci Rep. 2022 Jun 17;12(1):10207.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/35715570/
PMCID PMC9205954
Risk Stratification for Early-Onset Colorectal Cancer Using a Combination of Genetic and Environmental Risk Scores: An International Multi-Center Study

Authors Archambault AN, Jeon J, Lin Y. et al
Citation JNCI. 2022 Apr 11;114(4):528-539.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/35026030/
PMCID PMC9002285
Cancer Risk C (CR-C), a functional genomics test, is a sensitive and rapid test for germline mismatch repair deficiency

Authors Alim I, Loke J, Yam S. et al
Citation Genet Med. 2022 Sep;24(9):1821-1830.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/35616648/
PMCID PMC10072225

2021

DNA methylation-based signature of CD8+ tumor-infiltrating lymphocytes enables evaluation of immune response and prognosis in colorectal cancer

Authors Zou Q, Wang X, Ren D. et al
Citation J Immunother Cancer. 2021 Sep;9(9):e002671.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/34548385/
PMCID PMC8458312
Dual role of allele-specific DNA hypermethylation within the TERT promoter in cancer

Authors Lee DD, Komosa M, Sadhaman S, et al.
Citation J Clin Invest. 2021 Nov 1;131(21):e146915.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/34720085/
PMCID PMC8553568
Rare variants in the DNA pathway and the risk of colorectal cancer

Authors Matejcic M, Shaban HA, Quintana MW, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2021 Feb 24; cebp. 1457.2020.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/33627384/
PMCID PMC8102340
Tetranucleotide and Low Microsatellite Instability Are Inversely Associated with the CpG Island Methylator Phenotype in Colorectal Cancer

Authors Meessen S, Currey N, Jahan Z, et al.
Citation Cancers. 2021 Jul 14;13(14):3529.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/34298744/
PMCID PMC8308094
Salicylic Acid and Risk of Colorectal Cancer: A Two-Sample Mendelian Randomization Study

Authors Nounu A, Richmond RC, Stewart ID, et al.
Citation Nutrients. 2021 Nov 21;13(11):4164.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/34836419/
PMCID PMC8620763
An integrated mass spectrometry imaging and digital pathology workflow for objective detection of colorectal tumours by unique atomic signatures

Authors Paul B, Kysenius K, Hilton JB, et al.
Citation Chem Sci. 2021 Jun 29;12(30):10321-10333.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/34476052/
PMCID PMC8386113
Germline and Tumor Sequencing as a Diagnosit Tool to Resolve Suspected Lynch Syndrome

Authors Pope BJ, Clendenning M, Rosty C, et al.
Citation J Mol Diagn. 2021 Mar; 23(3):358-371.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/33383211/
PMCID PMC7927277
Associations of household income with health-related quality of life following a colorectal cancer diagnosis varies with neighborhood socioeconomic status

Authors Robinson JRM, Phipps AI, Barrington WE, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2021 Jul;30(7):1366-1374.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/33947657/
PMCID PMC8254776
Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report

Authors Seppälä TT, Dominguez-Valentin M, Crosbie EJ, et al.
Citation Eur J Cancer. 2021 May;148:124-133.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/33743481/
PMCID PMC8916840
Response to Li and Hopper.

Authors Thomas M, Sakoda LC, Hoffmeister M, et al.
Citation Am J Hum Genet. 2021 Mar 4;108(3):527-529.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/33667396/
PMCID PMC8008475
Genetically predicted circulating concentrations of micronutrients and risk of colorectal cancer among individuals of European descent: a Mendelian randomization study

Authors Tsilidis KK, Papadimitriou N, Dimou N, et al.
Citation Am J Clin Nutr. 2021 Mar 19;nqab003.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/33740060/
PMCID PMC8168352
Association Between Smoking and Molecular Subtypes of Colorectal Cancer

Authors Wang X, Amitay E, Harrison TA, et al.
Citation JNCI Cancer Spectr. 2021 Jun14;5(4):pkab056.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/34377935/
PMCID PMC8346704
A genome-wide search for determinants of survival in 1926 patients with advanced colorectal cancer with follow-up in over 22,000 patients

Authors Wills C, He Y, Summers MG, Lin Y, et al.
Citation Eur J Cancer. 2021 Nov 15;159:247-258.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/34794066/
PMCID PMC9132154
Genetically predicted physical activity levels are associated with lower colorectal cancer risk: a Mendelian randomisation study

Authors Zhang X, Theodoratou E, Li X, et al.
Citation Br J Cancer. 2021 Mar;124(7):1330-1338.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/33510439/
PMCID PMC8007642
Variation in the Risk of Colorectal Cancer for Lynch Syndrome: A retrospective family cohort study

Authors International Mismatch Repair Consortium.
Citation Lancet Oncol. 2021 Jul;22(7):1014-1022.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/34111421/
PMCID PMC8934577
DNA Methylation Signatures and the Contribution of Age-Associated Methylomic Drift to Carcinogenesis in Early-Onset Colorectal Cancer

Authors Joo JE, Clendenning M, Wong EM, et al.
Citation Cancers (Basel) 2021 May 25;13(11):2589.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/34070516/
PMCID PMC8199056
Assessment of a Polygenic Risk Score for Colorectal Cancer to Predict Risk of Lynch Syndrome Colorectal Cancer

Authors Jenkins MA, Buchanan DD, Lai J, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2021 May;30(5):895-903.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/33928216/
PMCID PMC8062848
Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report

Authors Dominguez-Valentin M, Crosbie EJ, Engel C, et al.
Citation Genet Med. 2021 Apr;23(4):705-712.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/33257847/
PMCID PMC8026395
Nongenetic Determinants of Risk for Early-Onset Colorectal Cancer

Authors Archambault AN, Lin Y, Jeon J, et al.
Citation JNCI Cancer Spectr. 2021 May 20;5(3):pkab029.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/34041438/
PMCID PMC8134523
Molecular and pathology features of colorectal tumors and patient outcomes are associated with Fusobacterium nucleatum and its subspecies animalis

Authors Borozan I, Zaidi SH, Harrison TA, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2021 Nov 4;cebp.EPI-21-0463-A.2021.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/34737207/
PMCID PMC8755593
Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals

Authors Chen H, Majumdar A, Wang L, et al.
Citation HGG Adv. 2021 Jul 8;2(3):100041.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/34355204/
PMCID PMC8336922
FamEvent: An R Package for Generating and Modeling Time-to-Event Data in Family Designs

Authors Choi YH, Briollais L, He W.
Citation J Stat Softw. 2021 Mar;97(7):10.18637/jss.v097.i07.
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Two-Sample Mendelian Randomization Analysis of Associations Between Periodontal Disease and Risk of Cancer

Authors Corlin L, Ruan M, Tsilidis KK, et al.
Citation JNCI Cancer Spectr. 2021 Apr 19;5(3):pkab037.
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Lack of an association between gallstone disease and bilirubin levels with risk of colorectal cancer: a Mendelian randomisation analysis

Authors Culliford R, Cornish AJ, Law PJ, et al.
Citation Br J Cancer. 2021 Jan 7.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/33414539/
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Circulating levels of testosterone, sex hormone binding globulin and colorectal cancer risk: observational and Mendelian randomization analysis

Authors Dimou N, Mori N, Harlid S, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2021 Apr 20;cebp.EPI-20-1690-E.2020.
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Causal effects of lifetime smoking on breast and colorectal cancer risk: Mendelian randomization study

Authors Dimou N, Yarmolinsky J, Bouras E, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2021 Mar 2;cebp.EPI-20-1218-E.2020.
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Smoking Behavior and Prognosis After Colorectal Cancer Diagnosis: A Pooled Analysis of 11 Studies

Authors Alwers E, Carr PR, Banbury B, et al.
Citation JNCI Cancer Spectr. 2021 Oct 5(5): pkab077.
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No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in MLH1 and MSH2: A Prospective Lynch Syndrome Database Study

Authors Dominguez-Valentin M, Plazzer JP, et al.
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Breast Cancer Risk Genes – Association Analysis in More than 113,000 Women

Authors Dorling L, Carvalho S, Allen J, et al.
Citation N Engl J Med. 2021 Feb 4;384(5):428-439.
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Evaluating the utility of tumour mutational signatures for identifying hereditary colorectal cancer and polyposis syndrome carriers

Authors Georgeson P, Pope BJ, Rosty C, et al.
Citation Gut. 2021 Jan 7. gutjnl-2019-320462.
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Genetically predicted circulating C-reactive protein concentration and colorectal cancer survival: A Mendelian randomization study

Authors Hua X, Dai JY, Lindström S, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2021 May 10:cebp.1848.2021.
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Association between post-treatment circulating biomarkers of inflammation and survival among stage II-III colorectal cancer patients

Authors Hua X, Kratz M, Malen RC, et al.
Citation Br J Cancer. 2021 Jul 6.
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Genetic variants associated with circulating C-reactive protein levels and colorectal cancer survival: Sex- and lifestyle factors- specific associations

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Citation Int J Cancer. 2021 Dec 9.
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Genetic architectures of proximal and distal colorectal cancer are partly distinct

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Citation Gut 2021 Feb 25;gutjnl-2020-321534.
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2020

Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk

Authors Thomas M, Sakoda LC, Hoffmeister M, et al.
Citation Am J Hum Genet. 2020 Jul 29:S0002-9297(20)30236-6.
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Genetic predictors of circulating 25-hydroxyvitamin D and prognosis after colorectal cancer

Authors Neumeyer S, Butterbach K, Banbury BL, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2020Mar 18.
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Genetic Variants in the Regulatory T cell-Related Pathway and Colorectal Cancer Prognosis

Authors Neumeyer S, Hua X, Seibold P, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2020 Dec;29(12):2719-2728.
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A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer

Authors Nounu A, Greenhough A, Heesom KJ, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2020 Dec 14;cebp.1176.2020.
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Physical activity and risks of breast and colorectal cancer: A Mendelian randomisation analysis

Authors Papadimitriou N, Dimou N, Tsilidis KK, et al.
Citation Nat Commun. 2020 Jan 30;11(1):597.
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A Latent Unknown Clustering Integrating Multi-Omics Data (LUCID) With Phenotypic Traits

Authors Peng C, Wang J, Asante I, et al.
Citation Bioinformatics. 2020 Feb 1;36(3):842-850.
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Association Between Molecular Subtypes of Colorectal Tumors and Patient Survival, Based on Pooled Analysis of 7 International Studies

Authors Phipps AI, Alwers E, Harrison T, et al.
Citation Gastroenterology. 2020 Jun;158(8):2158-2168.e4.
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The Impact of a Comprehensive Risk Prediction Model for Colorectal Cancer on a Population Screening Program

Authors Saya S, Emery JD, Dowty JG, et al.
Citation JNCI Cancer Spectrum. 2020 Oct; 4(5):
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Circulating Bilirubin Levels and Risk of Colorectal Cancer: Serological and Mendelian Randomization Analyses

Authors Seyed Khoei N, Jenab M, Murphy N, et al.
Citation BMC Med. 2020 Sep 3;18(1):229.
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Circulating Levels of Insulin-like Growth Factor 1 and Insulin-like GrowthFactor Binding Protein 3 Associate With Risk of Colorectal Cancer Based on Serologic and MendelianRandomization Analyses

Authors Murphy N, Carreras-Torres R, Song M, et al.
Citation Gastoenterology. 2020 Apr;158(5).
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Contribution of mRNA Splicing to Mismatch Repair Gene Sequence Variant Interpretation

Authors Thompson BA, Walters R, Parsons MT, et al.
Citation Front Genet. 2020; 11:798.
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Exploratory genome-wide interaction analysis of non-steroidal anti-inflammatory drugs and predicted gene expression on colorectal cancer risk

Authors Wang X, Su YR, Peterson PS, Bien S,et al
Citation Cancer Epidemiol Biomarkers Prev. 2020 Jul 10.
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Functional informed genome-wide interaction analysis of body mass index: diabetes and colorectal cancer risk

Authors Xia Z, Su YR, Petersen P, et al.
Citation Cancer Med. 2020 Mar 24.
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Telomere Maintenance Variants and Survival After Colorectal Cancer: Smoking- And Sex-Specific Associations

Authors Yin H, Hardikar S, Lindström S, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2020 Sep;29(9):1817-1824.
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Landscape of somatic mutations in colorectal cancer and their impact on survival

Authors Zaidi SH, Harrison TA, Phipps AI, et al.
Citation Nat Commun. 2020 Jul 20;11(1):3644.
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Assessment of Polygenic Architecture and Risk Prediction based on Common Variants Across Fourteen Cancers

Authors Zhang YD, Hurson AN, Zhang H, et al.
Citation Nat Commun. 2020 Jul 3;11(1):3353.
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A new comprehensive colorectal cancer risk prediction model incorporating family history, personal characteristics, and environmental factors

Authors Zheng Y, Hua X, Win AK, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2020 Mar;29(3):549-557.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/31932410/
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Height and Colorectal and Endometrial Cancer Risk for Persons with Lynch Syndrome

Authors Brouwer JGM, Newcomb PA, Bisseling TM, et al.
Citation Am J Epidemiol. 2020 Aug 17:kwwaa175.
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Intake of dietary fruit, vegetables, and fiber and risk of colorectal cancer according to molecular subtypes: A pooled analysis

Authors Hidaka A, Harrison TA, Cao Y, et al.
Citation Cancer Res. 2020 Aug 14:canres.0168.2020.
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Association of Body Mass Index With Colorectal Cancer Risk by Genome-Wide Variants

Authors Campbell PT, Lin Y, Bien SA, Figueiredo JC, et al.
Citation JNCI. 2020 Apr 23.
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Modifiable pathways for colorectal cancer: A mendelian randomisation analysis

Authors Cornish AJ, Law PJ, Timofeeva M, et al.
Citation Lancet Gastroenterol Hepatol. 2020 Jan;5(1):55-62.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/31668584/
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Circulating adipokine concentrations and risk of five obesity-related cancers: A Mendelian randomization study

Authors Dimou NL, Papadimitriou N, Mariosa D, et al.
Citation Int J Cancer. 2020 Oct 10.
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A general framework for functionally informed set-based analysis: Application to a large-scale colorectal cancer study

Authors Dong X, Su YR, Barfield R, et al.
Citation Plos Genetics. 2020 Aug 24;16(8):e1008947.
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Monoallelic NTHL1 Loss of Function Variants and Risk of Polyposis and Colorectal Cancer

Authors Elsayed FA, Grolleman JE, Ragunathan A, et al.
Citation Gastroenterology. 2020 Aug 26;S0016-5085(20)35113-1.
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Do the risks of Lynch syndrome-related cancers depend on the parent of origin of the mutation?

Authors Gemechu SD, van Vliet CM, Win AK, et al.
Citation Fam Cancer. 2020 Feb 27.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/32107660/
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Identifying Novel Susceptibility Genes for Colorectal Cancer Risk From a Transcriptome-Wide Association Study of 125,478 Subjects

Authors Guo X, Lin W, Wen W, Huyghe J, et al.
Citation Gastroenterology. 2020 Oct 12; S0016-5085(20)35243-4.
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Potential impact of family history-based screening guildelines on the detection of early-onset colorectal cancer

Authors Gupta S, Bharti B, Ahnen DJ, et al
Citation Cancer. 2020 Apr 20.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/32307706/
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Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study

Authors Bull CJ, Bell JA, Murphy N, et al.
Citation BMC Med. 2020 Dec 17;18(1):396.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/33327948/
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Limiting oxidative DNA damage reduces microbe-induced colitis-associated colorectal cancer

Authors Irrazabal T, Thakur BK, Kang M, et al.
Citation Nat Commun. 2020; 11:1802.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/32286276/
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Association between known risk factors and colorectal cancer risk in Indigenous people participating in the Ontario Familial Colon Cancer Registry

Authors Jamal S, Sheppard S, Cotterchio M.
Citation Curr Oncol. 2020 Aug;27(4):e395-e398.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/32905327/
PMCID PMC7467780
Hemochromatosis risk genotype is not associated with colorectal cancer or age at its diagnosis

Authors Jarvik GP, Wang X, Fontanillas P, et al.
Citation HGG Adv. 2020 Aug 25; 1(1):100010.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/35047832/
PMCID PMC8756515
Mendelian Randomization of Circulating Polyunsaturated Fatty Acids and Colorectal Cancer Risk

Authors Khankari NK, Banbury BL, Borges MC, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2020 Feb 12.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/32051193/
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Post-menopausal hormone therapy and colorectal cancer risk by molecularly-defined subtypes and tumor location

Authors Labadie JD, Harrison TA, Banbury B, et al.
Citation JNCI Cancer Spectrum. 2020 Oct;4(5).
PubMedLink https://pubmed.ncbi.nlm.nih.gov/32923935/
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Identification of Novel Loci and New Risk Variant in Known Loci for Colorectal Cancer Risk in East Asians

Authors Lu Y, Kweon SS, Cai Q, Tanikawa C, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2020 Feb;29(2):477-486.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/31826910/
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Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer

Authors Montazeri Z, Li X, Nyiraneza C, Ma X, et al.
Citation Gut. 2020 Aug;69(8).
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PMCID PMC7398467

2019

Cumulative Burden of Colorectal Cancer-Associated Genetic Variants Is More Strongly Associated With Early-onset vs Late-onset Cancer.

Authors Archambault AN, Su YR, Jeon J, et al.
Citation Gastroenterology. 2019 Dec 19.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/31866242/
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Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer.

Authors Bien SA, Su YR, Conti DV, et al.
Citation Hum Genet. 2019 Feb 28.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/30820706/
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Type 2 diabetes mellitus, blood cholesterol, triglycerideand colorectal cancer risk in Lynch syndrome.

Authors Dashti SG, Li WY, Buchanan DD, et al.
Citation Br J Cancer. 2019 Sep 25.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/31551580/
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Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database.

Authors Dominguez-Valentin M, Sampson JR, Seppälä TT, et al.
Citation Genet Med. 2019 Jul 24.
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PMCID PMC7371626
Telephone versus in-person colorectal cancer risk and screening intervention for first-degree relatives: A randomized controlled trial.

Authors Esplen MJ, Harrington S, Leung YW, et al.
Citation Cancer. 2019 Mar 12.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/30861097/
PMCID PMC6742581
Tumor mutational signatures in sebaceous skin lesions from individuals with Lynch syndrome.

Authors Georgeson P, Walsh MD, Clendenning M, et al.
Citation Mol Genet Genomic Med. 2019 Jun 4;e781.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/31162827/
PMCID PMC6625139
Discovery of common and rare genetic risk variants for colorectal cancer.

Authors Huyghe JR, Bien SA, Harrison TA, et al.
Citation Nat Genet. 2019 Jan;51(1):76-87.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/30510241/
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Ability of known susceptibility SNPs to predict colorectal cancer risk for persons with and without a family history.

Authors Jenkins MA, Win AK, Dowty JG, et al.
Citation Fam Cancer. 2019 Jun 17.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/31209717/
PMCID PMC6785388
Shared heritability and functional enrichment across six solid cancers.

Authors Jiang X, Finucane HK, Schumacher FR, et al.
Citation Nat Commun. 2019 Jan 25;10(1):431.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/30683880/
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Association analyses identify 31 new risk loci for colorectal cancer susceptibility.

Authors Law PJ, Timofeeva M, Fernandez-Rozadilla C, et al.
Citation Nat Commun. 2019 May 14;10(1):2154.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/31089142/
PMCID PMC6517433
Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer.

Authors Lu Y, Kweon SS, Tanikawa C, et al.
Citation Gastroenterology. 2019 Apr;156(5):1455-1466.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/30529582/
PMCID PMC6441622
DNA repair and cancer in colon and rectum: novel players in genetic susceptibility.

Authors Pardini B, Corrado A, Paolicchi E, et al.
Citation Int J Cancer. 2019 Jun 17.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/31209889/
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Genome-wide association study of circulating folate one-carbon metabolites.

Authors Wang J, Asante I, Baron JA, et al.
Citation Genet Epidemiol. 2019 Sep 10.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/31502714/
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Mendelian randomization analysis of C-reactive protein on colorectal cancer risk.

Authors Wang X, Dai JY, Albanes D, et al.
Citation Int J Epidemiol. 2018 Nov 21.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/30476131/
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Combined effect of modifiable and non-modifiable risk factors for colorectal cancer risk in a pooled analysis of 11 population-based studies.

Authors Wang X, O’Connell K, Jeon J, et al.
Citation BMJ Open Gastroenterol. 2019 Dec 2;6(1):e000339.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/31875139/
PMCID PMC6904202

2018

Symptom Severity and Quality of Life Among Long-Term Colorectal Cancer Survivors Compared with Matched Control Subjects: A Population-Based Study.

Authors Hart TL, Charles ST, Gunaratne M, et al.
Citation Dis Colon Rectum. 2018 Jan 24.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/29377871/
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Influence of Smoking, Body Mass Index, and Other Factors on the Preventive Effect of Nonsteroidal Anti-Inflammatory Drugs on Colorectal Cancer Risk.

Authors Wang X, Chan AT, Slattery ML, et al.
Citation Cancer Res. 2018 Aug 15;78(16):4790-4799.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/29921691/
PMCID PMC6095723
Cancer risks for PMS2-associated Lynch syndrome.

Authors ten Broeke SW, van der Klift H, Tops C, et al.
Citation J Clin Oncol. 2018 Oct 10;36(29):2961-2968.
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Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci.

Authors Tanskanen T, van den Berg L, Välimäki N, et al.
Citation Int J Cancer. 2018 Feb 1;142(3):540-546.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/28960316/
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A Mixed-Effects Model for Powerful Association Tests in Integrative Functional Genomics.

Authors Su YR, Di C, Bien S, et al.
Citation Am J Hum Genet. 2018 May 3;102(5):904-919.
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Interaction between polymorphisms in aspirin metabolic pathways, regular aspirin use and colorectal cancer risk: A case-control study in unselected white European populations.

Authors Sheth H, Northwood E, Ulrich CM, et al.
Citation PloS One. 2018 Feb 9;13(2):e0192223.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/29425227/
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Novel common genetic susceptibility loci for colorectal cancer.

Authors Schmit SL, Edlund CK, Schumacher FR, et al.
Citation J Natl Cancer Inst. 2019 Feb 1;111(2):146-157.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/29917119/
PMCID PMC6555904
Genetic susceptibility markers for a breast-colorectal cancer phenotype: Exploratory results from genome-wide association studies.

Authors Pande M, Joon A, Brewster AM, et al.
Citation PLoS One. 2018 Apr 26;13 (4): e0196245.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/29698419/
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DNA mismatch repair protein deficient non-neoplastic colonic crypts: a novel indicator of Lynch syndrome.

Authors Pai RK, Dudley B, Karloski E, et al.
Citation Mod Pathol. 2018 Jun 8.
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Mendelian randomisation study of age at menarche and age at menopause and the risk of colorectal cancer.

Authors Neumeyer S, Banbury BL, Arndt V, et al.
Citation Br J Cancer. 2018 Jun;118(12):1639-1647.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/29795306/
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Discussions about predictive genetic testing for Lynch syndrome: the role of health professionals and families in decisions to decline.

Authors Kanga-Parabia A, Gaff C, Flander L, et al.
Citation Fam Cancer. 2018 Feb 20.
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Cohort Profile: The Colon Cancer Family Registry Cohort (CCFRC).

Authors Jenkins MA, Win AK, Templeton AS, et al.
Citation Int J Epidemiol. 2018 Feb 27.
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Exploring causality in the association between circulating 25-hydroxyvitamin D and colorectal cancer risk: a large Mendelian randomisation study.

Authors He Y, Timofeeva M, Farrington SM, et al.
Citation BMC Med. 2018 Aug 14;16(1):142.
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PMCID PMC6090711
Association Between Intake of Red and Processed Meat and Survival in Patients With Colorectal Cancer in a Pooled Analysis.

Authors Carr PR, Banbury B, Berndt SI, et al.
Citation Clin Gastroenterol Hepatol. 2018 Nov 23. pii: S1542-3565(18)31279-5.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/30476588/
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RNF43 is mutated less frequently in Lynch Syndrome compared with sporadic microsatellite unstable colorectal cancers.

Authors Fennell LJ, Clendenning M, McKeone DM, et al.
Citation Fam Cancer. 2018 Jan;17(1):63-69.
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Genomic Characterization of Upper-Tract Urothelial Carcinoma in Patients with Lynch Syndrome.

Authors Donahue TF, Bagrodia A, Audenet F, et al.
Citation JCO Precision Oncology. 2018 Jan 23.
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Family history-based colorectal cancer screening in Australia: a modelling study of the costs, benefits and harms of different participation scenarios.

Authors Dillon M, Flander L, Buchanan DD, et al.
Citation Plos Medicine. 2018 Aug 16;15(8):e1002630.
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Physical activity and the risk of colorectal cancer in Lynch syndrome.

Authors Dashti SG, Win AK, Hardikar SS, et al.
Citation Int J Cancer. 2018 Jun 14.
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Diagnostics of Pleiotropy in Mendelian randomization Studies: Global and Individual Tests for Direct Effects.

Authors Dai JY, Peters U, Wang X, et al.
Citation Am J Epidemiol. 2018 Sep 5.
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Somatic mutations of the coding microsatellites within the beta-2-microglobulin gene in mismatch repair-deficient colorectal cancers and adenomas.

Authors Clendenning M, Huang A, Jayasekara H, et al.
Citation Fam Cancer. 2018 Jan;17(1):91-100.
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Laxative type in relation to colorectal cancer risk.

Authors Citronberg JS, Hardikar S, Phipps A, et al.
Citation Ann Epidemiol. 2018 Jul 9. pii: S1047-2797(18)30109-1.
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Leptin gene variants and colorectal cancer risk: Sex-specific associations.

Authors Chun KA, Kocarnik JM, Hardikar SS, et al.
Citation PLoS One. 2018 Oct 31;13(10):e0206519.
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Association of family history and survival in patients with colorectal cancer: a pooled analysis of eight epidemiologic studies.

Authors Chong DQ, Banbury BL, Phipps AI, et al.
Citation Cancer Med. 2018 May;7(5):2192-2199.
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Risks of Colorectal Cancer and Cancer-Related Mortality in Familial Colorectal Cancer Type X and Lynch Syndrome Families.

Authors Choi YH, Lakhal-Chaieb L, Kröl A, et al.
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Costs and outcomes of Lynch syndrome screening in the Australian colorectal cancer population.

Authors Cenin DR, Naber SK, Lansdorp-Vogelaar I, et al.
Citation J Gastroenterol Hepatol. 2018 Oct;33(10):1737-1744.
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2017

Choosing not to undergo predictive genetic testing for hereditary colorectal cancer syndromes: expanding our understanding of decliners and declining.

Authors Keogh LA, Niven H, Rutstein A, et al.
Citation J Behav Med. 2017 Aug;40(4):583-594.
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Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans.

Authors Wang H, Schmit SL, Haiman CA, et al.
Citation Int J Cancer. 2017 Jun 15;140(12):2728-2733.
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Genetic Variants in Epigenetic Pathways and Risks of Multiple Cancers in the GAME-ON Consortium.

Authors Toth R, Scherer D, Kelemen LE, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2017 Jan 23.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/28115406/
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How does genetic risk information for Lynch syndrome translate to risk management behaviours?

Authors Steel E, Robbins A, Jenkins M, et al.
Citation Hered Cancer Clin Pract. 2017 Jan 5;15:1.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/28070225/
PMCID PMC5217251
The dynamic DNA methylation landscape of the mutL homolog 1 shore is altered by MLH1-93G>A polymorphism in normal tissues and colorectal cancer.

Authors Savio AJ, Mrkonjic, Lemire M, et al.
Citation Clin. Epigenetics. 2017 Mar 9;9:26.
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Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer.

Authors Rodriguez-Broadbent H, Law PJ, Sud A, et al.
Citation Int J Cancer. 2017 Jun 15;140(12):2701-2708.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/28340513/
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Targeted sequencing of established and candidate colorectal cancer genes in the Colon Cancer Family Registry Cohort.

Authors Raskin L, Guo Y, Du L, et al.
Citation Oncotarget. 2017 Jun 21;8(55):93450-93463.
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Prediagnostic alcohol consumption and colorectal cancer survival: The Colon Cancer Family Registry.

Authors Phipps AI, Robinson JR, Campbell PT, et al.
Citation Cancer. 2017 May 15;123(6):1035-1043.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27861761/
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Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis.

Authors May-Wilson S, Sud A, Law PJ, et al.
Citation Eur J Cancer. 2017 Aug 19;84:228-238.
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Quantifying the Genetic Correlation between Multiple Cancer Types.

Authors Lindström S, Finucane H, Bulik-Sullivan B, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2017 Sep;26(9):1427-1435.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/28637796/
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Germline miRNA DNA variants and the risk of colorectal cancer by subtype.

Authors Lindor NM, Larson MC, DeRycke MS, et al.
Citation Genes Chromosomes Cancer. 2017 Mar;56(3):177-184.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27636879/
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Clinical verification of genetic results returned to research participants: findings from a Colon Cancer Family Registry.

Authors Laurino MY, Truitt AR, Tenney L, et al.
Citation Mol Genet Genomic Med. 2017 Nov;5(6):700-708.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/29178651/
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Long-term weight loss after colorectal cancer diagnosis is associated with lower survival: The Colon Cancer Family Registry.

Authors Kocarnik JM, Hua X, Hardikar S, et al.
Citation Cancer. 2017 Aug 25.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/28841225/
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Enrichment of colorectal cancer associations in functional regions: Insight for using epigenomics data in the analysis of whole genome sequence-imputed GWAS data.

Authors Bien SA, Auer PL, Harrison TA, et al.
Citation PLoS One. 2017 Nov 21;12(11):e0186518.
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PMCID PMC5697874
Timing of Aspirin and Other Nonsteroidal Anti-Inflammatory Drug Use Among Patients with Colorectal Cancer in Relation to Tumor Markers and Survival.

Authors Hua X, Phipps AI, Burnett-Hartman AN, et al.
Citation J Clin Oncol. 2017 Aug 20;35(24):2806-2813.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/28617623/
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Inherited variation in circadian rhythm genes and risks of prostate cancer and three other cancer sites in combined cancer consortia.

Authors Gu F, Zhang H, Hyland PL, et al.
Citation Int J Cancer. 2017 Nov 1;141(9):1794-1802.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/28699174/
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Testing for Gene-Environment Interactions Using a Prospective Family Cohort Design: Body Mass Index in Early and Later Adulthood and Risk of Breast Cancer.

Authors Dite GS, MacInnis RJ, Bickerstaffe A, et al.
Citation Am J Epidemiol. 2017 Mar 15;185(6):487-500.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/28399571/
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Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study.

Authors Dimitrakopoulou VI, Tsilidis KK, Haycock PC, et al.
Citation BMJ. 2017 Oct 31;359.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/29089348/
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Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study.

Authors Dienstmann R, Mason MJ, Sinicrope FA, et al.
Citation Ann Oncol. 2017 May 1;28(5):1023-1031.
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Targeted sequencing of 36 known or putative colorectal cancer susceptibility genes.

Authors DeRycke MS, Gunawardena S, Balcom JR, et al.
Citation Mol Genet Genomic Med. 2017 Jul 23;5(5):553-569.
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Alcohol Consumption and the Risk of Colorectal Cancer in Mismatch Repair Gene Mutation Carriers.

Authors Dashti SG, Buchanan DD, Jayasekara H, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2017 Mar;26(3):366-375.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27811119/
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Modeling of successive cancer risks in Lynch syndrome families in the presence of competing risks using copulas.

Authors Choi YH, Briollais L, Win AK, et al.
Citation Biometrics. 2017 Mar;73(1):271-282.
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Risk of colorectal cancer for carriers of a germ-line mutation in POLE or POLD1.

Authors Buchanan DD, Stewart JR, Clendenning M, et al.
Citation Genet Med. 2017 Nov 9.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/29120461/
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Lack of evidence for germline RNF43 mutations in patients with serrated polyposis syndrome from a large multinational study.

Authors Buchanan DD, Clendenning M, Zhuoer L, et al.
Citation Gut. 2017 Jun;66(6):1170-1172.
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Tumor testing to identify lynch syndrome in two Australian colorectal cancer cohorts.

Authors Buchanan DD, Clendenning M, Rosty C, et al.
Citation J Gastroenterol Hepatol. 2017 Feb;32(2):427-438.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27273229/
PMCID PMC5140773

2016

Risk Factors for Early-Onset and Very-Early-Onset Pancreatic Adenocarcinoma: A Pancreatic Cancer Case-Control Consortium (PanC4) Analysis.

Authors McWilliams RR, Maisonneuve P, Bamlet WR, et al.
Citation Pancreas. 2016 Feb;45(2):311-6.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26646264/
PMCID PMC4710562
Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk.

Authors Zeng C, Matsuda K, Jia WG, et al.
Citation Gastroenterology. 2016 Jun;150(7):1633-45.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26965516/
PMCID PMC4909543
Common variants in the obesity-associated genes FTO and MC4R are not associated with risk of colorectal cancer.

Authors Yang B, Thrift AP, Figueiredo JC, et al.
Citation Cancer Epidemiol. 2016 Oct;44:1-4.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27449576/
PMCID PMC5125024
Association of a let-7 miRNA binding region of TGFBR1 with hereditary mismatch repair proficient colorectal cancer (MSS HNPCC).

Authors Xicola RM, Bontu S, Doyle BJ, et al.
Citation Carcinogenesis. 2016 Aug;37(8):751-8.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27234654/
PMCID PMC4967215
Risk of extracolonic cancers for people with biallelic and monoallelic mutations in MUTYH.

Authors Win AK, Reece JC, Dowty JG, et al.
Citation Int J Cancer. 2016 Oct 1;139(7):1557-63.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27194394/
PMCID PMC5094810
Prevalence and penetrance of major genes and polygenes for colorectal cancer.

Authors Win AK, Jenkins MA, Dowty JG, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2016 Oct 31.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27799157/
PMCID PMC5336409
The Experience of Extended Bowel Resection in Individuals With a High Metachronous Colorectal Cancer Risk: A Qualitative Study.

Authors Steel EJ, Trainer AH, Heriott AG, et al.
Citation Oncol Nurs Forum. 2016 Jul 1;43(4):444-52.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27314187/
PMCID PMC5114664
Winner’s Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data.

Authors Shi J, Park JH, Duan J, et al.
Citation PLoS Genet. 2016 Dec 30;12(12):e1006493.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/28036406/
PMCID PMC5201242
Cholecystectomy and the risk of colorectal cancer by tumor mismatch repair deficiency status.

Authors Shang J, Reece JC, Buchanan DD, et al.
Citation Int J Colorectal Dis. 2016 Aug;31(8):1451-7.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27286977/
PMCID PMC4949040
A Cross-Cancer Genetic Association Analysis of the DNA Repair and DNA Damage Signaling Pathways for Lung, Ovary, Prostate, Breast, and Colorectal Cancer.

Authors Scarbrough PM, Weber RP, Iversen ES, et al.
Citation Cancer Epidemiol Biomarkers Prev 2016 Jan;25(1):193-200.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26637267/
PMCID PMC4713268
Promoter methylation of ITF2, but not APC, is associated with microsatellite instability in two populations of colorectal cancer patients.

Authors Savio AJ, Daftary D, Dicks E, et al.
Citation BMC Cancer. 2016 Feb 17;16(1):113.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26884349/
PMCID PMC4756469
GWASeq: targeted re-sequencing follow up to GWAS.

Authors Salomon PM, Li WG, Edlund CK, et al.
Citation BMC Genomics. 2016 Mar 3;17:176.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26940994/
PMCID PMC4776370
Germline mutations in PMS2 and MLH1 in individuals with solitary loss of PMS2 expression in colorectal carcinomas from the Colon Cancer Family Registry Cohort.

Authors Rosty C, Clendenning M, Walsh MD, et al.
Citation BMJ Open. 2016 Feb 19;6(2):e010293.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26895986/
PMCID PMC4762074
Knowledge and Uptake of Genetic Counseling and Colonoscopic Screening Among Individuals at Increased Risk for Lynch Syndrome and their Endoscopists from the Family Health Promotion Project.

Authors Patel SG, Ahnen DJ, Kinney AY, et al.
Citation Am J Gastroenterol. 2016 Feb;111(2):285-93.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26856748/
PMCID PMC5193129
Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease.

Authors Orlando G, Law PJ, Palin K, et al.
Citation Hum Mol Genet. 2016 Jun 1;25(11):2349-2359.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27005424/
PMCID PMC5081051
Quality of Life and Mortality of Long-Term Colorectal Cancer Survivors in the Seattle Colorectal Cancer Family Registry.

Authors Adams SV, Ceballos R, Newcomb PA.
Citation PLoS One. 2016 Jun 2;11(6):e0156534.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27253385/
PMCID PMC4890809
Clinicopathologic Risk Factor Distributions for MLH1 Promoter Region Methylation in CIMP-Positive Tumors.

Authors Levine AJ, Phipps AI, Baron JA, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2016 Jan;25(1):68-75.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26512054/
PMCID PMC4713308
SNP rs16906252C>T is an expression and methylation quantitative trait locus associated with an increased risk of developing MGMT-methylated colorectal cancer.

Authors Kuroiwa-Trzmielina J, Wang F, Rapkins RW, et al.
Citation Clin Cancer Res. 2016 Dec 15;22(24):6266-6277.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27267851/
PMCID PMC5143212
The Impact of Receiving Predictive Genetic Information about Lynch Syndrome on Individual Colonoscopy and Smoking Behaviors.

Authors Kim JS, Coyte PC, Cotterchio M, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2016 Nov;25(11):1524-1533.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27528600/
PMCID PMC5274544
Telomere structure and maintenance gene variants and risk of five cancer types.

Authors Karami S, Han Y, Pande M, et al.
Citation Int J Cancer. 2016 Dec 15;139(12):2655-2670.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27459707/
PMCID PMC5198774
Risk factors for metachronous colorectal cancer following a primary colorectal cancer: A prospective cohort study.

Authors Jayasekara H, Reece JC, Buchanan DD, et al.
Citation Int J Cancer. 2016. 139, 1081-1090.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27098183/
PMCID PMC4911232
Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer.

Authors Jarvis D, Mitchell JS, Law PJ, et al.
Citation Br J Cancer. 2016 Jul 12;115(2):266-72.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27336604/
PMCID PMC4947703
PMS2 monoallelic mutation carriers: the known unknown.

Authors Goodenberger ML, Thomas BC, Riegert-Johnson D, et al.
Citation Genet Med. 2016 Jan;18(1):13-9.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25856668/
PMCID PMC4834863
Genome-Wide Interaction Analyses between Genetic Variants and Alcohol Consumption and Smoking for Risk of Colorectal Cancer.

Authors Gong J, Hutter CM, Newcomb PA, et al.
Citation PLoS Genet. 2016 Oct 10;12(10):e1006296.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27723779/
PMCID PMC5065124
CYP24A1 variant modifies the association between use of oestrogen plus progestogen therapy and colorectal cancer risk.

Authors Garcia-Albeniz X, Rudolph A, Hutter C, et al.
Citation Br J Cancer. 2016 Jan 19;114(2):221-9.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26766742/
PMCID PMC4815813
Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

Authors Fehringer G, Kraft P, Pharoah PD, et al.
Citation Cancer Res. 2016 Sep 1;76(17):5103-14.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27197191/
PMCID PMC5010493
Nonsyndromic cleft lip with or without cleft palate and cancer: Evaluation of a possible common genetic background through the analysis of GWAS data.

Authors Dunkhase E, Ludwig KU, Knapp M, et al.
Citation Genom Data. 2016;10:22–29.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27630819/
PMCID PMC5013250
Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants.

Authors Du M, Jiao S, Bien S, et al.
Citation PLoS One. 2016 Jul 5;11(7):e0157521.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27379672/
PMCID PMC4933364
Multivitamin, calcium and folic acid supplements and the risk of colorectal cancer in Lynch syndrome.

Authors Chau R, Dashti SG, Ait Ouakrim D, et al.
Citation Int J Epidemiol. 2016 Jun;45(3):940-53.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/27063605/
PMCID PMC5697347
A Bayesian graphical model for genome-wide association studies (GWAS).

Authors Briollais L, Dobra A, Liu J, et al.
Citation Ann Appl Stat. 2016 Jun;10(2):786-811.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/33907591/
PMCID PMC8075301

2015

Mendelian randomization study of height and risk of colorectal cancer.

Authors Thrift AP, Gong J, Peters U, et al.
Citation Int J Epidemiol. 2015 Apr;44(2):662-72.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25997436/
PMCID PMC4481609
The effect of 5-fluorouracil/leucovorin chemotherapy on CpG methylation, or the confounding role of leukocyte heterogeneity: an illustration.

Authors Lemire M, Zaidi SH, Zanke BW, et al.
Citation Genomics. 2015 Dec;106(6):340-7.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26368860/
PMCID PMC4722538
Association of aspirin and NSAID use with risk of colorectal cancer according to genetic variants.

Authors Nan H, Hutter CM, Lin Y, et al.
Citation JAMA. 2015 Mar 17;313(11):1133-42.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25781442/
PMCID PMC4382867
Consequences of germline variation disrupting the constitutional translational initiation codon start sites of MLH1 and BRCA2: Use of potential alternative start sites and implications for predicting variant pathogenicity.

Authors Parsons MT, Whiley PJ, Beesley J, et al.
Citation Mol Carcinog. 2015 Jul;54(7):513-22.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24302565/
PMCID PMC4041856
PIK3CA Somatic Mutation Status in Relation to Patient and Tumor Factors in Racial/Ethnic Minorities with Colorectal Cancer.

Authors Phipps AI, Ahnen DJ, Cheng I, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2015 Jul;24(7):1046-51.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25994739/
PMCID PMC4490937
Association between molecular subtypes of colorectal cancer and patient survival.

Authors Phipps AI, Limburg PJ, Baron JA, et al.
Citation Gastroenterology. 2015 Jan;148(1):77-87.e2.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25280443/
PMCID PMC4274235
The Influence of Screening for Precancerous Lesions on Family-Based Genetic Association Tests: An Example of Colorectal Polyps and Cancer.

Authors Schmit SL, Figueiredo JC, Cortessis VK.
Citation Am J of Epidemiol. 2015 Oct 15;182(8):714-22.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26306664/
PMCID PMC4597802
Genome-wide association study of colorectal cancer identifies six new susceptibility loci.

Authors Schumacher FR, Schmit SL, Jiao S, et al.
Citation Nat Commun. 2015 Jul 7;6:7138.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26151821/
PMCID PMC4967357
Fertility after young-onset colorectal cancer: a study of subjects with Lynch syndrome.

Authors Stupart D, Win AK, Winship IM.
Citation Colorectal Dis. 2015 Sep;17(9):787-93.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25754680/
PMCID PMC4766107
Long-range epigenetic regulation is conferred by genetic variation located at thousands of independent loci.

Authors Lemire M, Zaidi SH, Ban M, et al.
Citation Nat Commun. 2015 Feb 26;6:6326.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25716334/
PMCID PMC4351585
Mendelian randomization study of body mass index and colorectal cancer risk.

Authors Thrift AP, Gong J, Peters U, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2015 Jul;24(7):1024-31.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25976416/
PMCID PMC4490960
A high-resolution copy-number variation resource for clinical and population genetics.

Authors Uddin M, Thiruvahindrapuram B, Walker S, et al.
Citation Genet Med. 2015 Sep;17(9):747-52.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25503493/
PMCID PMC4752593
Association of the colorectal CpG island methylator phenotype with molecular features, risk factors and family history.

Authors Weisenberger DJ, Levine AJ, Long TI, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2015 Mar;24(3):512-9.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25587051/
PMCID PMC4355081
Role of tumour molecular and pathology features to estimate colorectal cancer risk for first-degree relatives.

Authors Win AK, Buchanan DD, Rosty C, et al.
Citation Gut. 2015 Jan;64(1):101-10.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24615377/
PMCID PMC4180004
Genetic variants within the hTERT gene and the risk of colorectal cancer in Lynch syndrome.

Authors Win AK, Clendenning M, Crawford W, et al.
Citation Genes Cancer. 2015 Nov; 6(11-12): 445–451.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26807197/
PMCID PMC4701223
Risk of colorectal cancer for people with a mutation in both a MUTYH and a DNA mismatch repair gene.

Authors Win AK, Reece JC, Buchanan DD, et al.
Citation Fam Cancer. 2015 Dec;14(4):575-83.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26202870/
PMCID PMC4631636
Germline TP53 mutations in patients with early-onset colorectal cancer in the Colon Cancer Family Registry.

Authors Yurgelun MB, Masciari S, Joshi VA, et al.
Citation JAMA Oncol. 2015 May;1(2):214-21.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26086041/
PMCID PMC4465271
Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study.

Authors Zhang C, Doherty JA, Burgess S, et al.
Citation Hum Mol Genet. 2015 Sep 15;24(18):5356-66.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26138067/
PMCID PMC4550826
Long-term psychosocial and behavioral adjustment in individuals receiving genetic test results in Lynch syndrome.

Authors Esplen JM, Won J, Aronson M, et al.
Citation Clin Genet. 2015 Jun;87(6):525-32.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25297893/
PMCID PMC4391982
A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer.

Authors Al-Tassan NA, Whiffin N, Hosking FJ, et al.
Citation Sci Rep. 2015 May 20;5:10442.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25990418/
PMCID PMC4438486
Red meat intake, NAT2, and risk of colorectal cancer: A pooled analysis of 11 studies.

Authors Ananthakrishnan AN, Du M, Berndt SI, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2015 Jan;24(1):198-205.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25342387/
PMCID PMC4294960
Lynch syndrome and cervical cancer.

Authors Antill YC, Dowty JG, Win AK, et al.
Citation Int J Cancer. 2015 Dec 1;137(11):2757-61.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26077226/
PMCID PMC4573262
Association between body mass index and mortality for colorectal cancer survivors: overall and by tumor molecular phenotype.

Authors Campbell PT, Newton CC, Newcomb PA, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2015 Aug;24(8):1229-38.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26038390/
PMCID PMC4526409
Determining the familial risk distribution of colorectal cancer: a data mining approach.

Authors Chau R, Jenkins MA, Buchanan DD, et al.
Citation Fam Cancer. 2015 Dec 17.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26681340/
PMCID PMC4803603
Common colorectal cancer risk alleles contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP.

Authors Cheng TH, Gorman M, Martin L, et al.
Citation Eur J Hum Genet. 2015 Feb;23(2):260-3.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24801760/
PMCID PMC4140766
Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.

Authors Cheng TH, Thompson D, Painter J, et al.
Citation Sci Rep. 2015 Dec 1;5:17369.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26621817/
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Female Hormonal Factors and the Risk of Endometrial Cancer in Lynch Syndrome.

Authors Dashti SG, Chau R, Quakrim DA, et al.
Citation JAMA. 2015 Jul 7;314(1):61-71.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26151267/
PMCID PMC4688894
Aspirin, Ibuprofen, and the Risk of Colorectal Cancer in Lynch Syndrome.

Authors Ait Ouakrim D, Dashti SG, Chau R, et al.
Citation J Natl Cancer Inst. 2015 Jun 24;107(9).
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PMCID PMC4651105
Mutation Spectrum and Risk of Colorectal Cancer in African American Families with Lynch Syndrome.

Authors Guindalini RS, Win AK, Gulden C, et al.
Citation Gastroenterology. 2015 Nov;149(6):1446-53.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26248088/
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Prediagnostic Physical Activity and Colorectal Cancer Survival: Overall and Stratified by Tumor Characteristics.

Authors Hardikar S, Newcomb PA, Campbell PT, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2015 Jul;24(7):1130-7.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25976417/
PMCID PMC4491038
Childhood Cancers in families with and without Lynch syndrome.

Authors Heath JA, Reece JC, Buchanan DD, et al.
Citation Fam Cancer. 2015 Dec;14(4):545-51.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25963852/
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Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer.

Authors Hung RJ, Ulrich CM, Goode EL, et al.
Citation J Natl Cancer Inst. 2015 Aug 29;107(11).
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26319099/
PMCID PMC4675100
Meat intake, cooking methods, dietary carcinogens, and colorectal cancer risk: findings from the Colorectal Cancer Family Registry.

Authors Joshi AD, Kim A, Lewinger JP, et al.
Citation Cancer Med. 2015 Jun;4(6):936-52.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25846122/
PMCID PMC4472216
Comparison of Prediction Models for Lynch Syndrome Among Individuals with Colorectal Cancer.

Authors Kastrinos F, Ojha RP, Leenen C, et al.
Citation J Natl Cancer Inst. 2015 Nov 18;108(2).
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26582061/
PMCID PMC4862416
Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer.

Authors Khalili H, Gong J, Brenner H, et al.
Citation Carcinogenesis. 2015 Sep;36(9):999-1007.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26071399/
PMCID PMC4573660
A genome-wide association study for colorectal cancer identifies a risk locus in 14q23.1.

Authors Lemire M, Qu C, Loo LWM, et al.
Citation Hum Genet. 2015 Nov;134(11-12):1249-62.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/26404086/
PMCID PMC4687971

2014

Tumour MLH1 promoter region methylation testing is an effective prescreen for Lynch Syndrome (HNPCC).

Authors Newton K, Jorgensen NM, Wallace AJ, et al.
Citation J Med Genet. 2014 Dec;51(12):789-96.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25280751/
PMCID PMC5159427
Dietary N-nitroso compounds and risk of colorectal cancer: a case-control study in Newfoundland and Labrador and Ontario, Canada.

Authors Zhu Y, Wang PP, Zhao J, et al.
Citation Br J Nutr. 2014 Mar 28;111(6):1109-17.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24160559/
PMCID PMC4339287
Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk.

Authors Zhang B, Jia WH, Matsuda K, et al.
Citation Nat Genet. 2014 Jun;46(6):533-42.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24836286/
PMCID PMC4068797
Risk of colorectal cancer for carriers of mutations in MUTYH, with and without a family history of cancer.

Authors Win AK, Dowty JG, Cleary SP, et al.
Citation Gastroenterology. 2014 May;146(5):1208-11.e1-5.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24444654/
PMCID PMC3992182
Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.

Authors Whiffin N, Hosking FJ, Farrington SM, et al.
Citation Hum Mol Genet. 2014 Sep 1;23(17):4729-37.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24737748/
PMCID PMC4133584
Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VT11A.

Authors Wang H, Burnett T, Kono S, et al.
Citation Nat Commun. 2014 Aug 8;5:4613.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25105248/
PMCID PMC4180879
Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database.

Authors Thompson BA, Spurdle AB, Plazzer JP, et al.
Citation Nat Genet. 2014 Feb;46(2):107-15.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24362816/
PMCID PMC4294709
Fertility and apparent genetic anticipation in Lynch syndrome.

Authors Stupart D, Win AK, Jenkins M, et al.
Citation Fam Cancer. 2014 Sep;13(3):369-74.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24677027/
PMCID PMC4357528
Characterisation of Familial Colorectal Cancer Type X, Lynch syndrome, and non-familial colorectal cancer.

Authors Shiovitz S, Copeland WK, Passarelli MN, et al.
Citation Br J Cancer. 2014 Jul 29;111(3):598-602.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24918813/
PMCID PMC4119982
A novel colorectal cancer risk locus at 4q32.2 identified from an international genome-wide association study.

Authors Schmit SL, Schumacher FR, Edlund CK, et al.
Citation Carcinogenesis. 2014 Nov;35(11):2512-9.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25023989/
PMCID PMC4271131
Genetic variation in UGT genes modify the associations of NSAIDs with risk of colorectal cancer: Colon Cancer Family Registry.

Authors Scherer D, Koepl LM, Poole EM, et al.
Citation Genes Chromosomes Cancer. 2014 Jul;53(7):568-78.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24677636/
PMCID PMC4326223
High prevalence of mismatch repair deficiency in prostate cancers diagnosed in mismatch repair gene mutation carriers from the Colon Cancer Family Registry.

Authors Rosty C, Walsh MD, Lindor NM, et al.
Citation Fam Cancer. 2014 Dec;13(4):573-82.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25117503/
PMCID PMC4329248
Genetic Variation in prostaglandin synthesis and related pathways, NSAID use, and colorectal cancer risk in the Colon Cancer Family Registry.

Authors Resler AJ, Makar KW, Heath L, et al.
Citation Carcinogenesis. 2014 Sep;35(9):2121-6.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24908683/
PMCID PMC4146420
Family History of Colorectal Cancer is not Associated with Colorectal Cancer Survival Regardless of Microsatellite Instability Status.

Authors Phipps A, Ahnen DJ, Campbell PT, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2014 Aug;23(8):1700-4.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24891550/
PMCID PMC4119483
Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer-associated variants.

Authors Peltekova VD, Lemire M, Qazi AM, et al.
Citation Int J Cancer. 2014 May 15;134(10):2330-41.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24154973/
PMCID PMC3949167
No association between germline variation in catechol-O-methyltransferase and colorectal cancer survival in postmenopausal women.

Authors Passarelli MN, Newcomb PA, Makar KW, et al.
Citation Menopause. 2014 Apr;21(4):415-20.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23880798/
PMCID PMC3865220
A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age.

Authors Ahsan H, Halpern J, Kibriya MG, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2014 Apr;23(4):658-69.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24493630/
PMCID PMC3990360
A randomized trial to increase colonoscopy screening in members of high risk families in the Colorectal Cancer Family Registry and Cancer Genetics Network.

Authors Lowery JT, Horick N, Kinney AY, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2014 Apr;23(4):601-10.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24501379/
PMCID PMC3976708
Colorectal cancer and self-reported tooth agenesis.

Authors Lindor NM, Win AK, Gallinger S, et al.
Citation Hered Cancer Clin Pract. 2014 Mar 10;12(1):7.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24607150/
PMCID PMC3975307
How do researchers manage genetic results in practice? The experience of the multinational Colon Cancer Family Registry.

Authors Keogh LA, Fisher D, Sheinfeld Gorin S, et al.
Citation J Community Genet. 2014 Apr;5(2):99-108.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23703702/
PMCID PMC3955463
Gene-environment interaction involving recently identified colorectal cancer susceptibility loci.

Authors Kantor ED, Hutter CM, Minnier J, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2014 Sep;23(9):1824-33.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24994789/
PMCID PMC4209726
Communication of genetic test results to family and health-care providers following disclosure of research results.

Authors Graves KD, Sinicrope PS, Esplen MJ, et al.
Citation Genet Med. 2014 Apr;16(4):294-301.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24091800/
PMCID PMC4009372
Functional normalization of 450k methylation array data improves replication in large cancer studies.

Authors Fortin JP, Labbe A, Lemire M, et al.
Citation Genome Biol. 2014 Dec 3;15(12):503.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25599564/
PMCID PMC4283580
Perceived versus predicted risks of colorectal cancer and self-reported colonoscopies by members of mismatch repair gene mutation-carrying families who have declined genetic testing.

Authors Flander L, Speirs-Bridge A, Rutstein A, et al.
Citation J Genet Couns. 2014 Feb;23(1):79-88.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23748873/
PMCID PMC3838501
Genome-wide diet-gene interaction analyses for risk of colorectal cancer.

Authors Figueiredo JC, Hsu L, Hutter CM, et al.
Citation PLoS Genet. 2014 Apr 17;10(4):e1004228.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24743840/
PMCID PMC3990510
No evidence of gene-calcium interactions in genome-wide analysis of colorectal cancer risk.

Authors Du M, Zhang X, Hoffmeister M, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2014 Dec;23(12):2971-6.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25192705/
PMCID PMC4257872
Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia.

Authors Cheng I, Kocarnik JM, Dumitrescu L, et al.
Citation Gut. 2014 May;63(5):800-7.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23935004/
PMCID PMC3918490
Diabetes, antidiabetic medications, and pancreatic cancer risk: an analysis from the International Pancreatic Cancer Case-Control Consortium.

Authors Bosetti C, Rosato V, Li D, et al.
Citation Ann Oncol. 2014 Oct;25(10):2065-72.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25057164/
PMCID PMC4176453
A genome-wide association study of anorexia nervosa.

Authors Boraska V, Franklin C , Floyd JAB, et al.
Citation Mol Psychiatry. 2014 Oct;19(10):1085-94.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24514567/
PMCID PMC4325090
The association of telomere length with colorectal cancer differs by the age of cancer onset.

Authors Boardman LA, Litzelman K, Seo S, et al.
Citation Clin Transl Gastroenterol. 2014 Mar 6;5:e52.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24598784/
PMCID PMC3972691
Does risk of endometrial cancer for women without a germline mutation in a DNA mismatch repair gene depend on family history of endometrial cancer or colorectal cancer?

Authors Bharati R, Jenkins MA, Lindor NM, et al.
Citation Gynecol Oncol. 2014 May;133(2):287-92.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24631449/
PMCID PMC4016812

2013

Two-phase and family-based designs for next-generation sequencing studies.

Authors Thomas DC, Yang Z, Yang F.
Citation Front Genet. 2013 Dec 13;4:276.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24379824/
PMCID PMC3861783
CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer.

Authors Ling H, Spizzo R, Atlasi Y, et al.
Citation Genome Res. 2013 Sep;23(9):1446-61.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23796952/
PMCID PMC3759721
Integrated analysis of genome-wide copy number alterations and gene expression in microsatellite stable, CpG island methylator phenotype-negative colon cancer.

Authors Loo LW, Tiirikainen M, Cheng I, et al.
Citation Genes Chromosomes Cancer. 2013 May;52(5):450-66.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23341073/
PMCID PMC4019504
Colorectal cancer survival by location and microsatellite status: data from the Colon Cancer Family Registries and their implications.

Authors Lynch PM.
Citation Dis Colon Rectum. 2013 Aug;56(8):935-6.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23838860/
PMCID NA
COX-1 (PTGS1) and COX-2 (PTGS2) polymorphisms, NSAID interactions, and risk of colon and rectal cancers in two independent populations.

Authors Makar KW, Poole EM, Resler AJ, et al.
Citation Cancer Causes Control. 2013 Dec;24(12):2059-75.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24022467/
PMCID PMC3913564
Allergies and risk of pancreatic cancer: a pooled analysis from the Pancreatic Cancer Case-Control Consortium.

Authors Olson SH, Hsu M, Satagopan JM, et al.
Citation Am J Epidemiol. 2013 Sep 1;178(5):691-700.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23820785/
PMCID PMC3755648
Common single-nucleotide polymorphisms in the estrogen receptor β promoter are associated with colorectal cancer survival in postmenopausal women.

Authors Passarelli MN, Phipps AI, Potter JD, et al.
Citation Cancer Res. 2013 Jan 15;73(2):767-75.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23149914/
PMCID PMC3588850
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-wide Meta-analysis.

Authors Peters U, Jiao S, Schumacher FR, et al.
Citation Gastroenterology. 2013 Apr;144(4):799-807.e24.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23266556/
PMCID PMC3636812
KRAS-mutation status in relation to colorectal cancer survival: the joint impact of correlated tumour markers.

Authors Phipps AI, Buchanan DD, Makar KW, et al.
Citation Br J Cancer. 2013 Apr 30;108(8):1757-64.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23511557/
PMCID PMC3668469
Colon and rectal cancer survival by tumor location and microsatellite instability: The Colon Cancer Family Registry.

Authors Phipps AI, Lindor NM, Jenkins MA, et al.
Citation Dis Colon Rectum. 2013 Aug;56(8):937-44.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23838861/
PMCID PMC3708260
Multiplicity and molecular heterogeneity of colorectal carcinomas in individuals with serrated polyposis.

Authors Rosty C, Walsh MD, Walters RJ, et al.
Citation Am J Surg Pathol. 2013 Mar;37(3):434-42.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23211288/
PMCID PMC3567207
IÎºBKÎ² and NFÎºB1, NSAID use and risk of colorectal cancer in the Colon Cancer Family Registry.

Authors Seufert BL, Poole EM, Whitton J, et al.
Citation Carcinogenesis. 2013 Jan;34(1):79-85.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23002237/
PMCID PMC3534188
Polymorphisms in genes related to one-carbon metabolism are not related to pancreatic cancer in PanScan and PanC4.

Authors Leenders M, Bhattacharjee S, Vineis P, et al.
Citation Cancer Causes Control. 2013 Mar;24(3):595-602.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23334854/
PMCID PMC4127987
BRAFV600E immunohistochemistry facilitates universal screening of colorectal cancers for Lynch syndrome.

Authors Toon CW, Walsh MD, Chou A, et al.
Citation Am J Surg Pathol. 2013 Oct;37(10):1592-602.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23797718/
PMCID PMC3773060
Lynch syndrome-associated breast cancers do not overexpress chromosome 11-encoded mucins.

Authors Walsh MD, Cummings MC, Pearson SA, et al.
Citation Mod Pathol. 2013 Jul;26(7):944-54.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23370770/
PMCID PMC4204018
Association between hypermethylation of DNA repetitive elements in white blood cell DNA and early-onset colorectal cancer.

Authors Walters RJ, Williamson EJ, English DR, et al.
Citation Epigenetics. 2013 Jul;8(7):748-55.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23804018/
PMCID PMC3781194
Fine-mapping of genome-wide association study-identified risk loci for colorectal cancer in African Americans.

Authors Wang H, Haiman CA, Burnett T, et al.
Citation Hum Mol Genet. 2013 Dec 15;22(24):5048-55.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23851122/
PMCID PMC3836473
Genetic variation in the inflammation and innate immunity pathways and colorectal cancer risk.

Authors Wang H, Taverna D, Stram DO, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2013 Nov;22(11):2094-101.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24045924/
PMCID PMC3836607
Germline variants and advanced colorectal adenomas: adenoma prevention with celecoxib trial genome-wide association study.

Authors Wang J, Carvajal-Carmona LG, Chu JH, et al.
Citation Clin Cancer Res. 2013 Dec 1;19(23):6430-7.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24084763/
PMCID PMC4037290
Deciphering the genetic architecture of low-penetrance susceptibility to colorectal cancer.

Authors Whiffin N, Dobbins SE, Hosking FJ, et al.
Citation Hum Mol Genet. 2013 Dec 15;22(24):5075-82.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23904454/
PMCID PMC3836483
Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers?

Authors Win AK, Hopper JL, Buchanan DD, et al.
Citation Eur J Cancer. 2013 May;49(7):1578-87.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23434150/
PMCID PMC3625445
Risks of colorectal and other cancers after endometrial cancer for women with lynch syndrome.

Authors Win AK, Lindor NM, Winship I, et al.
Citation J Natl Cancer Inst. 2013 Feb 20;105(4):274-9.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23385444/
PMCID PMC3576323
Risk of metachronous colon cancer following surgery for rectal cancer in mismatch repair gene mutation carriers.

Authors Win AK, Parry S, Parry B, et al.
Citation Ann Surg Oncol. 2013 Jun;20(6):1829-36.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23358792/
PMCID PMC4041733
Dietary patterns and colorectal cancer recurrence and survival: a cohort study.

Authors Zhu Y, Wu H, Wang PP, et al.
Citation BMJ Open. 2013 Feb 7;3(2). pii: e002270.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23396503/
PMCID PMC3586110
Germline Mutations in the Polyposis-Associated Genes BMPR1A, SMAD4, PTEN, MUTYH and GREM1 Are Not Common in Individuals with Serrated Polyposis Syndrome.

Authors Clendenning M, Young JP, Walsh MD, et al.
Citation PLoS One. 2013 Jun 21;8(6):e66705.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23805267/
PMCID PMC3689730
Survival after inflammatory bowel disease-associated colorectal cancer in the Colon Cancer Family Registry.

Authors Adams SV, Ahnen DJ, Baron JA, et al.
Citation World J Gastroenterol. 2013 Jun 7;19(21):3241-8.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23745025/
PMCID PMC3671075
Screening participation for people at increased risk of colorectal cancer due to family history: a systematic review and meta-analysis.

Authors Ait Ouakrim D, Lockett T, Boussioutas A, et al.
Citation Fam Cancer. 2013 Sep;12(3):459-72.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23700069/
PMCID NA
Germline HOXB13 p.Gly84Glu mutation and risk of colorectal cancer.

Authors Akbari MR, Anderson LN, Buchanan DD, et al.
Citation Cancer Epidemiol. 2013 Aug;37(4):424-7.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23541221/
PMCID PMC3684005
Genetic variants in vitamin d pathway genes and risk of pancreas cancer; results from a population-based case-control study in ontario, Canada.

Authors Anderson LN, Cotterchio M, Knight JA, et al.
Citation PLoS One. 2013 Jun 24;8(6):e66768.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23826131/
PMCID PMC3691295
Ulcer, gastric surgery and pancreatic cancer risk: an analysis from the International Pancreatic Cancer Case-Control Consortium (PanC4).

Authors Bosetti C, Lucenteforte E, Bracci PM, et al.
Citation Ann Oncol. 2013 Nov;24(11):2903-10.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23970016/
PMCID PMC3811904
Family history of colorectal cancer in BRAF p.V600E-mutated colorectal cancer cases.

Authors Buchanan DD, Win AK, Walsh MD, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2013 May;22(5):917-26.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23462926/
PMCID PMC4024397
Human papillomavirus DNA is rarely detected in colorectal carcinomas and not associated with microsatellite instability: the Seattle Colon Cancer Family Registry.

Authors Burnett-Hartman AN, Feng Q, Popov V, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2013 Feb;22(2):317-9.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23250932/
PMCID PMC3565050
Much of the genetic risk of colorectal cancer is likely to be mediated through susceptibility to adenomas.

Authors Carvajal-Carmona LG, Zauber AG, Jones AM, et al.
Citation Gastroenterology. 2013 Jan;144(1):53-5.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/22999960/
PMCID PMC3572711
Innate immunity gene polymorphisms and the risk of colorectal neoplasia.

Authors Chang CM, Chia VM, Gunter MJ, et al.
Citation Carcinogenesis. 2013 Nov;34(11):2512-20.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23803696/
PMCID PMC3810838
Absence of PMS2 mutations in Colon-CFR participants whose colorectal cancers demonstrate unexplained loss of MLH1 expression.

Authors Clendenning M, Macrae FA, Walsh MD, et al.
Citation Clin Genet. 2013 Jun;83(6):591-3.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23017166/
PMCID PMC3557751
Detection of large scale 3′ deletions in the PMS2 gene amongst Colon-CFR participants: have we been missing anything?

Authors Clendenning M, Walsh MD, Gelpi JB, et al.
Citation Fam Cancer. 2013 Sep;12(3):563-6.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23288611/
PMCID PMC3639299
Phospholipase A2G1B polymorphisms and risk of colorectal neoplasia.

Authors Abbenhardt C, Poole EM, Kulmacz RJ, et al.
Citation Int J Mol Epidemiol Genet. 2013 Sep 12;4(3):140-9.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24046806/
PMCID PMC3773565
Telomere length varies by DNA extraction method: implications for epidemiologic research.

Authors Cunningham JM, Johnson RA, Litzelman K, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2013 Nov;22(11):2047-54.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/24019396/
PMCID PMC3827976
Identification of novel variants in colorectal cancer families by high-throughput exome sequencing.

Authors DeRycke MS, Gunawardena SR, Middha S, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2013 Jul;22(7):1239-51.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23637064/
PMCID PMC3704223
Cancer risks for MLH1 and MSH2 mutation carriers.

Authors Dowty JG, Win AK, Buchanan DD, et al.
Citation Hum Mutat. 2013 Mar;34(3):490-7.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23255516/
PMCID PMC3887142
Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42,103 individuals.

Authors Dunlop MG, Tenesa A, Farrington SM, et al.
Citation Gut. 2013 Jun;62(6):871-81.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/22490517/
PMCID PMC5105590
Genetic Predictors of Circulating 25-Hydroxyvitamin D and Risk of Colorectal Cancer.

Authors Hiraki LT, Qu C, Hutter CM, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2013 Nov;22(11):2037-46.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23983240/
PMCID PMC3818310
Receptivity and preferences in cancer risk reduction lifestyle programs: A survey of colorectal cancer family members.

Authors Howell LA, Brockman TA, Sinicrope PS, et al.
Citation J Behav Health. 2013; 2(4): 279-290.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/25606348/
PMCID PMC4297662
Interaction of polymorphisms in mitotic regulator genes with cigarette smoking and pancreatic cancer risk.

Authors Jang JH, Cotterchio M, Borgida A, et al.
Citation Mol Carcinog. 2013 Nov;52 Suppl 1:E103-9.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23908141/
PMCID PMC4533929
Genetic variations in SMAD7 are associated with colorectal cancer risk in the Colon Cancer Family Registry.

Authors Jiang X, Castelao JE, Vandenberg D, et al.
Citation PLoS One. 2013;8(4):e60464.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23560096/
PMCID PMC3616155
SBERIA: set-based gene-environment interaction test for rare and common variants in complex diseases.

Authors Jiao S, Hsu L, Bezieau S, et al.
Citation Genet Epidemiol. 2013 Jul;37(5):452-64.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/23720162/
PMCID PMC3713231
Comparison of the clinical prediction model PREMM(1,2,6) and molecular testing for the systematic identification of Lynch syndrome in colorectal cancer.

Authors Kastrinos F, Steyerberg EW, Balmaña J, et al.
Citation Gut. 2013 Feb;62(2):272-9.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/22345660/
PMCID PMC3470824

2012

Calibration of multiple in silico tools for predicting pathogenicity of mismatch repair gene missense substitutions.

Authors Thompson BA, Greenblatt MS, Vallee MP, et al.
Citation Hum Mutat. 2013 Jan;34(1):255-65.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/22949387/
PMCID PMC4318556
Meta-analysis of new genome-wide association studies of colorectal cancer risk.

Authors Peters U, Hutter CM, Hsu L, et al.
Citation Hum Genet. 2012 Feb;131(2):217-34.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/21761138/
PMCID PMC3257356
BRAF mutation status and survival after colorectal cancer diagnosis according to patient and tumor characteristics.

Authors Phipps AI, Buchanan DD, Makar KW, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2012 Oct;21(10):1792-8.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/22899730/
PMCID PMC3467328
A comparison of approaches for association studies of polymorphisms and colorectal cancer risk.

Authors Ramsey SD, Holmes RS, McDermott CL, et al.
Citation Colorectal Dis. 2012 Sep;14(9):e573-86.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/22390411/
PMCID PMC3471808
Vitamin D intake is negatively associated with promoter methylation of the Wnt antagonist gene DKK1 in a large group of colorectal cancer patients.

Authors Rawson JB, Sun Z, Dicks E, et al.
Citation Nutr Cancer. 2012;64(7):919-28.
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Citation Am J Surg Pathol 2012 Jun;36(6):876-82.
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A population-based study of prevalence and adherence trends in average risk colorectal cancer screening, 1997 to 2008.

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Citation Cancer Epidemiol Biomarkers Prev. 2012 Feb;21(2):347-50.
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Association of total energy intake and macronutrient consumption with colorectal cancer risk: results from a large population-based case-control study in Newfoundland and Labrador and Ontario, Canada.

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Citation Nutr J. 2012 Mar 26;11:18.
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Reported intake of selected micronutrients and risk of colorectal cancer: results from a large population-based case-control study in Newfoundland, Labrador and Ontario, Canada.

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Citation Anticancer Res. 2012 Feb;32(2):687-96.
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A multifactorial likelihood model for MMR gene variant classification incorporating probabilities based on sequence bioinformatics and tumor characteristics: a report from the Colon Cancer Family Registry.

Authors Thompson BA, Goldgar DE, Paterson C, et al.
Citation Hum Mutat. 2013 Jan;34(1):200-9.
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Correlation of tumour BRAF mutations and MLH1 methylation with germline mismatch repair (MMR) gene mutation status: a literature review assessing utility of tumour features for MMR variant classification.

Authors Parsons MT, Buchanan DD, Thompson B, et al.
Citation J Med Genet. 2012 Mar;49(3):151-7.
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Immunohistochemical testing of conventional adenomas for loss of expression of mismatch repair proteins in Lynch syndrome mutation carriers: a case series from the Australasian site of the Colon Cancer Family Registry.

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Citation Mod Pathol. 2012 May;25(5):722-30.
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Citation Int J Cancer. 2012 Apr 15;130(8):1898-907.
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Identification of constitutional MLH1 epimutations and promoter variants in colorectal cancer patients from the Colon Cancer Family Registry.

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Risks of primary extracolonic cancers following colorectal cancer in lynch syndrome.

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Colorectal and Other Cancer Risks for Carriers and Noncarriers From Families With a DNA Mismatch Repair Gene Mutation: A Prospective Cohort Study.

Authors Win AK, Young JP, Lindor NM, et al.
Citation J Clin Oncol. 2012 Mar 20;30(9):958-64.
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The Australasian Colorectal Cancer Family Registry: Reducing the impact of colorectal cancer.

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Citation Med J Aust 2012; 197 (9): 480-481.
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Interaction between alcohol drinking and obesity in relation to colorectal cancer risk: a case-control study in Newfoundland and Labrador, Canada.

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Citation BMC Public Health. 2012 Feb 1;12:94.
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Cancer risks for the relatives of colorectal cancer cases with a methylated MLH1 promoter region: data from the Colorectal Cancer Family Registry.

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Citation Cancer Prev Res (Phila). 2012 Feb;5(2):328-35.
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Authors Ait Ouakrim D, Lockett T, Boussioutas A, et al.
Citation Cancer Causes Control. 2012 Nov;23(11):1853-64.
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Citation Nat Genet. 2012 May 27;44(7):770-6.
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Citation Cancer Epidemiol Biomarkers Prev. 2012 Nov;21(11):1974-85.
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Characterization of Gene-Environment Interactions for Colorectal Cancer Susceptibility Loci.

Authors Hutter CM, Chang-Claude J, Slattery ML, et al.
Citation Cancer Res. 2012 Apr 15;72(8):2036-44.
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PMCID PMC3374720
Genetic variants in carcinogen-metabolizing enzymes, cigarette smoking and pancreatic cancer risk.

Authors Jang JH, Cotterchio M, Borgida A, et al.
Citation Carcinogenesis. 2012 Apr;33(4):818-27.
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PMCID PMC3324443
Letter: Kaplan-Meier failure estimate for metachronous colorectal cancer risk is clinically relevant.

Authors Jenkins MA, Gurrin LC, Parry S.
Citation Gut 2012;61:5 783-784 Published Online First: 24 October 2011.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/NA/
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Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer.

Authors Jia WH, Zhang B, Matsuo K, et al.
Citation Nat Genet. 2013 Feb;45(2):191-6.
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Genome-wide search for gene-gene interactions in colorectal cancer.

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Citation PLoS One. 2012;7(12):e52535.
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The TERT variant rs2736100 is associated with colorectal cancer risk.

Authors Kinnersley B, Migliorini G, Broderick P, et al.
Citation Br J Cancer. 2012 Sep 4;107(6):1001-8.
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Screening practices of unaffected people at familial risk of colorectal cancer.

Authors Ait Ouakrim D, Boussioutas A, Lockett T, et al.
Citation Cancer Prev Res (Phila). 2012 Feb;5(2):240-7.
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cis-Expression QTL analysis of established colorectal cancer risk variants in colon tumors and adjacent normal tissue.

Authors Loo LW, Cheng I, Tiirikainen M, et al.
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Lessons learned from the Family Health Promotion Project.

Authors Lowery JT, Ahnen DJ.
Citation Colorectal Cancer, June 2012, Vol. 1, No. 3, Pages 193-195.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/NA/
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The Family Health Promotion Project (FHPP): design and baseline data from a randomized trial to increase colonoscopy screening in high risk families.

Authors Lowery JT, Marcus A, Kinney A, et al.
Citation Contemp Clin Trials. 2012 Mar;33(2):426-35.
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Informatics and data quality at collaborative multicenter Breast and Colon Cancer Family Registries.

Authors McGarvey PB, Ladwa S, Oberti M, et al.
Citation J Am Med Inform Assoc. 2012 Jun;19(e1):e125-8.
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The Effect of a Multifaceted Efficacy Intervention on Exercise Behavior in Relatives of Colon Cancer Patients.

Authors McGowan EL, Prapavessis H, Campbell N, et al.
Citation Int J Behav Med. 2012 Dec;19(4):550-62.
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The germline MLH1 K618A variant and susceptibility to Lynch syndrome-associated tumors.

Authors Medeiros F, Lindor NM, Couch FJ.
Citation J Mol Diagn. 2012 May-Jun;14(3):264-73.
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Performance of PREMM(1,2,6), MMRpredict, and MMRpro in detecting Lynch syndrome among endometrial cancer cases.

Authors Mercado RC, Hampel H, Kastrinos F, et al.
Citation Genet Med. 2012 Jul;14(7):670-80.
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Identification of Lynch syndrome among patients with colorectal cancer.

Authors Moreira L, Balaguer F, Lindor N, et al.
Citation JAMA. 2012 Oct 17;308(15):1555-65.
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Citation Epidemiology. 2012 Mar;23(2):308-10.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/22252410/
PMCID PMC3299289

2011

Cancer: Lynch syndrome–how should colorectal cancer be managed?

Authors Vasen HF, de Vos tot Nederveen Cappel WH.
Citation Nat Rev Gastroenterol Hepatol. 2011 Apr;8(4):184-6.
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Authors Rawson JB, Manno M, Mrkonjic M, et al.
Citation Carcinogenesis. 2011 May;32(5):741-7.
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Promoter methylation of Wnt5a is associated with microsatellite instability and BRAF V600E mutation in two large populations of colorectal cancer patients.

Authors Rawson JB, Mrkonjic M, Daftary D, et al.
Citation Br J Cancer. 2011 Jun 7;104(12):1906-12.
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Authors Roberts A, Nancarrow D, Clendenning M, et al.
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Authors Rumilla K, Schowalter KV, Lindor NM, et al.
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Calcium and vitamin D and risk of colorectal cancer: results from a large population-based case-control study in Newfoundland and Labrador and Ontario.

Authors Sun Z, Wang PP, Roebothan B, et al.
Citation Can J Public Health. 2011 Sep-Oct;102(5):382-9.
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PMCID PMC6973686
Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer.

Authors Tomlinson IP, Carvajal-Carmona LG, Dobbins SE, et al.
Citation PLoS Genet. 2011 Jun;7(6):e1002105.
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Dependence of colorectal cancer risk on the parent-of-origin of mutations in DNA mismatch repair genes.

Authors van Vliet CM, Dowty JG, van Vliet JL, et al.
Citation Hum Mutat. 2011 Feb;32(2):207-12.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/21120946/
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Prediagnostic smoking history, alcohol consumption, and colorectal cancer survival: The Seattle Colon Cancer Family Registry.

Authors Phipps AI, Baron J, Newcomb PA.
Citation Cancer. 2011 Nov 1;117(21):4948-57.
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PMCID PMC3138819
Germline PKHD1 mutations are protective against colorectal cancer.

Authors Ward CJ, Wu Y, Johnson RA, et al.
Citation Hum Genet. 2011 Mar;129(3):345-9.
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Lynch syndrome: barriers to and facilitators of screening and disease management.

Authors Watkins KE, Way CY, Fiander JJ, et al.
Citation Hered Cancer Clin Pract. 2011 Sep 7;9:8.
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Cancer risks for monoallelic MUTYH mutation carriers with a family history of colorectal cancer.

Authors Win AK, Cleary SP, Dowty JG, et al.
Citation Int J Cancer. 2011 Nov 1;129(9):2256-62.
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Body mass index in early adulthood and endometrial cancer risk for mismatch repair gene mutation carriers.

Authors Win AK, Dowty JG, Antill YC, et al.
Citation Obstet Gynecol. 2011 Apr;117(4):899-905.
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Body mass index in early adulthood and colorectal cancer risk for carriers and non-carriers of germline mutations in DNA mismatch repair genes.

Authors Win AK, Dowty JG, English DR, et al.
Citation Br J Cancer. 2011 Jun 28;105(1):162-9.
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Association between monoallelic MUTYH mutation and colorectal cancer risk: a meta-regression analysis.

Authors Win AK, Hopper JL, Jenkins MA.
Citation Fam Cancer. 2011 Mar;10(1):1-9.
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Determining the frequency of de novo germline mutations in DNA mismatch repair genes.

Authors Win AK, Jenkins MA, Buchanan DD, et al.
Citation J Med Genet. 2011 Aug;48(8):530-4.
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Cigar and pipe smoking, smokeless tobacco use and pancreatic cancer: an analysis from the International Pancreatic Cancer Case-Control Consortium (PanC4).

Authors Bertuccio P, La Vecchia C, Silverman DT, et al.
Citation Ann Oncol. 2011 Jun;22(6):1420-6.
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PMCID PMC3139985
Common colorectal cancer risk variants in SMAD7 are associated with survival among prediagnostic nonsteroidal anti-inflammatory drug users: a population-based study of postmenopausal women.

Authors Passarelli MN, Coghill AE, Hutter CM, et al.
Citation Genes Chromosomes Cancer. 2011 Nov;50(11):875-86.
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Metachronous colorectal cancer risk for mismatch repair gene mutation carriers: the advantage of more extensive colon surgery.

Authors Parry S, Win AK, Parry B, et al.
Citation Gut. 2011 Jul;60(7):950-7.
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Pancreatic cancer and a novel MSH2 germline alteration.

Authors Lindor NM, Petersen GM, Spurdle AB, et al.
Citation Pancreas. 2011 Oct;40(7):1138-40.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/21926548/
PMCID PMC3425611
Prevalence of Alternations in DNA mismatch repair gene alterations in a population-based sample of young-onset colorectal cancer patients.

Authors Limburg PJ, Harmsen WS, Chen HH, et al.
Citation Clin Gastroenterol Hepatol. 2011 Jun;9(6):497-502.
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PMCID PMC3058119
The PREMM(1,2,6) model predicts risk of MLH1, MSH2, and MSH6 germline mutations based on cancer history.

Authors Kastrinos F, Steyerberg EW, Mercado R, et al.
Citation Gastroenterology. 2011 Jan;140(1):73-81.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/20727894/
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Genotype-environment interactions in microsatellite stable/microsatellite instability-low colorectal cancer: results from a genome-wide association study.

Authors Figueiredo JC, Lewinger JP, Song C, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2011 May;20(5):758-66.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/21357381/
PMCID PMC3089660
Development and Validation of an Instrument to Measure the Impact of Genetic Testing on Self-Concept in Lynch Syndrome (LS).

Authors Esplen MJ, Stuckless N, Wong J, et al.
Citation Clin Genet. 2011 Nov;80(5):415-23.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/21883167/
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Genetic variation in inflammatory pathways is related to colorectal cancer survival.

Authors Coghill AE, Newcomb PA, Poole EM, et al.
Citation Clin Cancer Res. 2011 Nov 15;17(22):7139-47.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/21976545/
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Pre-diagnostic NSAID use but not hormone therapy is associated with improved colorectal cancer survival in women.

Authors Coghill AE, Newcomb PA, Chia VM, et al.
Citation Br J Cancer. 2011 Mar 1;104(5):763-8.
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Prediagnostic non-steroidal anti-inflammatory drug use and survival after diagnosis of colorectal cancer.

Authors Coghill AE, Newcomb PA, Campbell PT, et al.
Citation Gut. 2011 Apr;60(4):491-8.
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Mutation deep within an intron of MSH2 causes Lynch syndrome.

Authors Clendenning M, Buchanan DD, Walsh MD, et al.
Citation Fam Cancer. 2011 Jun;10(2):297-301.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/21360204/
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Quality Assessment and Correlation of Microsatellite Instability and Immunohistochemical Markers among Population- and Clinic-Based Colorectal Tumors Results from the Colon Cancer Family Registry.

Authors Cicek MS, Lindor NM, Gallinger S, et al.
Citation J Mol Diagn. 2011 May;13(3):271-81.
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Fine-mapping of colorectal cancer susceptibility loci at 8q23.3, 16q22.1 and 19q13.11: refinement of association signals and use of in silico analysis to suggest functional variation and unexpected candidate target genes.

Authors Carvajal-Carmona LG, Cazier JB, Jones AM, et al.
Citation Hum Mol Genet. 2011 Jul 15;20(14):2879-88.
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Meta-analysis of 8q24 for seven cancers reveals a locus between NOV and ENPP2 associated with cancer development.

Authors Brisbin AG, Asmann YW, Song H, et al.
Citation BMC Med Genet. 2011 Dec 5;12:156.
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Management of pancreatic adenocarcinoma in Ontario, Canada: a population-based study using novel case ascertainment.

Authors Borgida AE, Ashamalla S, Al-Sukhni W, et al.
Citation Can J Surg. 2011 Feb;54(1):54-60.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/21251433/
PMCID PMC3038358

2010

Parent of origin effects on age at colorectal cancer diagnosis.

Authors Lindor NM, Rabe KG, Petersen GM, et al.
Citation Int J Cancer. 2010 Jul 15;127(2):361-6.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/19904757/
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On combining family-based and population-based case-control data in association studies.

Authors Zheng Y, Heagerty PJ, Hsu L.
Citation Biometrics. 2010 Dec;66(4):1024-33.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/20163402/
PMCID PMC3038246
Tobacco smoking and colorectal cancer: a population-based case-control study in Newfoundland and Labrador.

Authors Zhao J, Halfyard B, Roebothan B, et al.
Citation Can J Public Health. 2010 Jul-Aug;101(4):281-9.
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Risk factors: Hyperplastic polyposis syndrome and risk of colorectal cancer.

Authors Young JP, Parry S.
Citation Nat Rev Gastroenterol Hepatol. 2010 Nov;7(11):594-5.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/21042338/
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Lynch syndrome-associated breast cancers: clinicopathologic characteristics of a case series from the Colon Cancer Family Registry.

Authors Walsh MD, Buchanan DD, Cummings MC, et al.
Citation Clin Cancer Res. 2010 Apr 1;16(7):2214-24.
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A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants.

Authors Theodoratou E, Campbell H, Tenesa A, et al.
Citation Br J Cancer. 2010 Dec 7;103(12):1875-84.
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Pickled meat consumption and colorectal cancer (CRC): a case-control study in Newfoundland and Labrador, Canada.

Authors Squires J, Roebothan B, Buehler S, et al.
Citation Cancer Causes Control. 2010 Sep;21(9):1513-21.
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Lower gastrointestinal tract cancer predisposition syndromes.

Authors Shah NB, Lindor NM.
Citation Hematol Oncol Clin North Am. 2010 Dec;24(6):1229-52.
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Will Knowledge of Gene-based Colorectal Cancer Disease Risk Influence Quality of Life and Screening Behavior? Findings from a Population-based Study.

Authors Ramsey S, Blough D, McDermott C, et al.
Citation Public Health Genomics. 2010;13(1):1-12.
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Genetic variation in the vitamin D receptor (VDR) and the vitamin D-binding protein (GC) and risk for colorectal cancer: results from the Colon Cancer Family Registry.

Authors Poynter JN, Jacobs ET, Figueiredo JC, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2010 Feb;19(2):525-36.
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A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33.

Authors Petersen GM, Amundadottir L, Fuchs CS, et al.
Citation Nat Genet. 2010 Mar;42(3):224-8.
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Smoking and colorectal cancer in Lynch syndrome: results from the Colon Cancer Family Registry and the University of Texas M.D. Anderson Cancer Center.

Authors Pande M, Lynch PM, Hopper JL, et al.
Citation Clin Cancer Res. 2010 Feb 15;16(4):1331-9.
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Risk of endometrial cancer for women diagnosed with HNPCC-related colorectal carcinoma.

Authors Obermair A, Youlden DR, Young JP, et al.
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Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer.

Authors Mrkonjic M, Roslin NM, Greenwood CM, et al.
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Colon cancer information as a source of exercise motivation in first- and second-degree relatives of colon cancer patients.

Authors McGowan E, Prapavessis H.
Citation Psychology, Health, & Medicine. 2010 Dec;15(6):729-41.
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Molecular Characteristics of Early-onset Colorectal Cancer According to Detailed Anatomical Locations: Comparison to Later-onset Cases

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Elucidating the Risk of Colorectal Cancer for Variants in Hereditary Colorectal Cancer Genes

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Elucidating the Risk of Colorectal Cancer for Variants in Hereditary Colorectal Cancer Genes

Authors Mahmood K, Thomas M, Qu C, et al, and Peters U.
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DNA Mismatch Repair Gene Variant Classification: Evaluating the Utility of Somatic Mutations and Mismatch Repair Deficient Colonic Crypts and Endometrial Glands

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Combining Asian-European Genome-Wide Association Studies of Colorectal Cancer Improves Risk Prediction Across Race and Ethnicity

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Molecular Characteristics of Early-onset Colorectal Cancer According to Detailed Anatomical Locations: Comparison to Later-onset Cases

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Citation Am J Gastroenterol. 2023 Apr 1;118(4):712-726.
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Beyond GWAS of Colorectal Cancer: Evidence of Interaction with Alcohol Consumption and Putative Causal Variant for the 10q24.2 Region

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Genetic regulation of DNA methylation yields novel discoveries in GWAS of colorectal cancer

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Body Mass Index, sex, non-steroidal anti-inflammatory drug medications, smoking and alcohol are differentially associated with World Health Organisation criteria and colorectal cancer risk in people with Serrated Polyposis Syndrome: an Australian case-control study

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A tumor focused approach to resolving the etiology of DNA mismatch repair deficient tumors classified as suspected Lynch syndrome

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Prognostic role of detailed colorectal location and tumor molecular features: analyses of 13,101 colorectal cancer patients including 2994 early-onset cases

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Genetic Predictors for Fecal Propionate and Butyrate-Producing Microbiome Pathway Are Not Associated with Colorectal Cancer Risk: A Mendelian Randomization Analysis

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Genome-Wide Analyses Characterize Shared Heritability Among Cancers and Identify Novel Cancer Susceptibility Regions

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Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

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Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

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Genome-wide interaction study with smoking for colorectal cancer risk identifies novel genetic loci related to tumor suppression, inflammation and immune response

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Risk Stratification for Early-Onset Colorectal Cancer Using a Combination of Genetic and Environmental Risk Scores: An International Multi-Center Study

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Should health care providers have a duty to warn family members of individuals with an HNPCC-predisposing mutation? A survey of patients from the Ontario Familial Colon Cancer Registry.

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Variation in plasma insulin-like growth factor-1 and insulin-like growth factor binding protein-3: genetic factors.

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PubMedLink https://pubmed.ncbi.nlm.nih.gov/15896925/
PMCID NA
Variation in plasma insulin-like growth factor-1 and insulin-like growth factor binding protein-3: personal and lifestyle factors (United States).

Authors Morimoto LM, Newcomb PA, White E, et al.
Citation Cancer Causes Control. 2005 Oct;16(8):917-27.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/16132801/
PMCID NA
Insulin-like growth factor polymorphisms and colorectal cancer risk.

Authors Morimoto LM, Newcomb PA, White E, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2005 May;14(5):1204-11.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/15894673/
PMCID NA
Molecular predictors of lymph node metastasis in colon cancer: increased risk with decreased thymidylate synthase expression.

Authors Artinyan A, Essani R, Lake J, et al.
Citation J Gastrointest Surg. 2005 Dec;9(9):1216-21; discussion 1221.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/16332476/
PMCID NA
Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: Familial Colorectal Cancer Type X.

Authors Lindor NM, Rabe K, Petersen GM, et al.
Citation JAMA. 2005 Apr 27;293(16):1979-85.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/15855431/
PMCID PMC2933042
Identifying target populations for screening or not screening using logic regression.

Authors Janes H, Pepe M, Kooperberg C.
Citation Stat Med. 2005 May 15;24(9):1321-38.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/15568185/
PMCID NA
Isolated loss of PMS2 expression in colorectal cancers: frequency, patient age, and familial aggregation.

Authors Gill S, Lindor NM, Burgart LJ, et al.
Citation Clin Cancer Res. 2005 Sep 15;11(18):6466-71.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/16166421/
PMCID NA
Association between colonic screening, subject characteristics, and stage of colorectal cancer.

Authors Fazio L, Cotterchio M, Manno M, et al.
Citation Am J Gastroenterol. 2005 Nov;100(11):2531-9.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/16279911/
PMCID NA
Colorectal screening is associated with reduced colorectal cancer risk: a case-control study within the population-based Ontario Familial Colorectal Cancer Registry.

Authors Cotterchio M, Manno M, Klar N, et al.
Citation Cancer Causes Control. 2005 Sep;16(7):865-75.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/16132797/
PMCID NA
Environmental risk factors and colorectal neoplasia: Recent developments.

Authors Chia V, Newcomb PA.
Citation Current Colorectal Cancer Reports. 2005;1(2):67-72.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/NA/
PMCID NA
Conversion analysis for mutation detection in MLH1 and MSH2 in patients with colorectal cancer.

Authors Casey G, Lindor NM, Papadopoulos N, et al.
Citation JAMA. 2005 Feb 16;293(7):799-809.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/15713769/
PMCID PMC2933041
Use of microsatellite instability and immunohistochemistry testing for the identification of individuals at risk for Lynch syndrome.

Authors Baudhuin LM, Burgart LJ, Leontovich O.
Citation Fam Cancer. 2005;4(3):255-65.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/16136387/
PMCID NA

2004

Evidence for an association between JC virus and colorectal neoplasia.

Authors Boland CR, Bigler J, Newcomb PA, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2004 Dec;13(12):2285-6; author reply 2286.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/15598796/
PMCID NA
Association between biallelic and monoallelic germline MYH mutations and colorectal cancer risk.

Authors Croitoru ME, Cleary SP, Di Nicola N, et al.
Citation J Natl Cancer Inst. 2004;96(21):1631-4.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/15523092/
PMCID NA
The incidence of colorectal cancer following a negative screening sigmoidoscopy: implications for screening interval.

Authors Doria-Rose VP, Levin TR, Selby JV, et al.
Citation Gastroenterology. 2004; 127:714-722.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/15362026/
PMCID NA
BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum.

Authors Kambara T, Simms LA, Whitehall VL, et al.
Citation Gut. 2004 Aug;53(8):1137-44.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/15247181/
PMCID PMC1774130
Role of inherited defects of MYH in the development of sporadic colorectal cancer.

Authors Kambara T, Whitehall VL, Spring KJ, et al.
Citation Genes Chromosomes Cancer. 2004 May;40(1):1-9.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/15034862/
PMCID NA
Colorectal tumour microsatellite instability test results: perspectives from patients.

Authors Lindor NM, Sloan J, Goldberg R, et al.
Citation Hered Cancer Clin Pract. 2004 May 15;2(2):69-75.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/20233473/
PMCID PMC2839997
Recognition of genetic syndromes in families with suspected hereditary colon cancer syndromes.

Authors Lindor NM.
Citation Clin Gastroenterol Hepatol. 2004 May;2(5):366-75.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/15118973/
PMCID NA
Reasons given by relatives of colorectal cancer patients for not undergoing screening.

Authors Madlensky L, Esplen MJ, Goel V.
Citation Prev Med. 2004 Oct;39(4):643-8.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/15351528/
PMCID NA
No evidence of an association of JC virus and colon neoplasia.

Authors Newcomb PA, Bush AC, Stoner GL, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2004 Apr;13(4):662-6.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/15066935/
PMCID NA
Limitations of the odds ratio in gauging the performance of a diagnostic, prognostic, or screening marker.

Authors Pepe MS, Janes H, Longton G, et al.
Citation Am J Epidemiol. 2004 May 1;159(9):882-90.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/15105181/
PMCID NA
Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability.

Authors Umar A, Boland CR, Terdiman JP, et al.
Citation J Natl Cancer Inst. 2004 Feb 18;96(4):261-8.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/14970275/
PMCID PMC2933058
MYH mutations in patients with attenuated and classic polyposis and with young-onset colorectal cancer without polyps.

Authors Wang L, Baudhuin LM, Boardman LA, et al.
Citation Gastroenterology. 2004 Jul;127(1):9-16. Erratum in: Gastroenterology. 2004 Nov;127(5):1651.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/15236166/
PMCID NA

2003

The experience of loss and anticipation of distress in colorectal cancer patients undergoing genetic testing.

Authors Esplen MJ, Urquhart C, Butler K, et al.
Citation J Psychosom Res. 2003 Nov;55(5):427-35.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/14581097/
PMCID NA
The APC E1317Q variant in adenomatous polyps and colorectal cancers.

Authors Hahnloser D, Peterson GM, Rabe K, et al.
Citation Cancer Epidemiol Biomarkers Prev. 2003 Oct;12(10):1023-8.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/14578138/
PMCID NA
Frequency of loss of hMLH1 expression in colorectal carcinoma increases with advancing age.

Authors Kakar S, Burgart LJ, Thibodeau SN, et al.
Citation Cancer. 2003 Mar 15;97(6):1421-7.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/12627505/
PMCID NA
Relatives of colorectal cancer patients: factors associated with screening behavior.

Authors Madlensky L, Esplen MJ, Gallinger S, et al.
Citation Am J Prev Med. 2003 Oct;25(3):187-94.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/14507524/
PMCID NA
A comparison of self-reported colorectal cancer screening with medical records.

Authors Madlensky L, McLaughlin J, Goel V.
Citation Cancer Epidemiol Biomarkers Prev. 2003 Jul;12(7):656-9.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/12869407/
PMCID NA
Selection bias in the assessment of gene-environment interaction in case-control studies.

Authors Morimoto LM, White E, Newcomb PA.
Citation Am J Epidemiol. 2003 Aug 1;158(3):259-63.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/12882948/
PMCID NA
Agreement between proxy- and case-reported information obtained using the self-administered Ontario Familial Colon Cancer Registry epidemiologic questionnaire.

Authors Nadalin V, Cotterchio M, McKeown-Eyssen G.
Citation Chronic Dis Can. 2003 Winter;24(1):1-8.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/12757630/
PMCID NA
Long-term efficacy of sigmoidoscopy in the reduction of colorectal cancer incidence.

Authors Newcomb PA, Storer B, Morimoto LM, et al.
Citation J Natl Cancer Inst. 2003 Apr 16;95(8):622-5.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/12697855/
PMCID NA
Attitudes towards genetic screening for predisposition to colon cancer among cancer patients, their relatives, and members of the community Results of focus group interviews.

Authors Ramsey SD, Wilson S, Spencer A, et al.
Citation Community Genet. 2003;6(1):29-36.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/12748436/
PMCID NA
Lymph node retrieval and assessment in stage II colorectal cancer: a population-based study.

Authors Wright FC, Law CH, Last L, et al.
Citation Ann Surg Oncol. 2003 Oct;10(8):903-9.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/14527909/
PMCID NA
Validation of family history data in cancer family registries.

Authors Ziogas A, Anton-Culver H.
Citation Am J Prev Med. 2003 Feb;24(2):190-8.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/12568826/
PMCID NA

2002

A population-based study of the extent of surgical resection of potentially curable colon cancer.

Authors Easson AM, Cotterchio M, Crosby JA, et al.
Citation Ann Surg Oncol. 2002 May;9(4):380-7.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/11986190/
PMCID NA
Distinction between familial and sporadic forms of colorectal cancer showing DNA microsatellite instability.

Authors Jass JR, Walsh MD, Barker M, et al.
Citation Eur J Cancer. 2002 May;38(7):858-66.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/11978509/
PMCID NA
Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors.

Authors Lindor NM, Burgart LJ, Leontovich O, et al.
Citation J Clin Oncol. 2002 Feb 15;20(4):1043-8.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/11844828/
PMCID NA
Ascertainment bias in family-based case-control studies.

Authors Siegmund KD, Langholz B.
Citation Am J Epidemiol. 2002 May 1;155(9):875-80.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/11978593/
PMCID NA
Mutation searching in colorectal cancer studies: experience with a denaturing high pressure liquid chromatography system for exon-by-exon scanning of tumour suppressor genes.

Authors Young J, Barker M, Fraser L, et al.
Citation Pathology. 2002 Dec;34(6):529-33.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/12555990/
PMCID NA

2001

Validity of proxy reports obtained using the Ontario Familial Colon Cancer Registry epidemiologic questionnaire.

Authors Nadalin V, Cotterchio M, McKeown-Eyssen G, et al.
Citation Am J Epidemiol. 2001;153:S88.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/NA/
PMCID NA
Stratified case sampling and the use of family controls.

Authors Siegmund KD, Langholz B.
Citation Genet Epidemiol. 2001 Apr;20(3):316-27.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/11255241/
PMCID NA
HPP1: a transmembrane protein-encoding gene commonly methylated in colorectal polyps and cancers.

Authors Young J, Biden KG, Simms LA, et al.
Citation Proc Natl Acad Sci USA. 2001 Jan 2;98(1):265-70.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/11120884/
PMCID PMC14579
Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: parallel pathways of tumorigenesis.

Authors Young J, Simms LA, Biden KG, et al.
Citation Am J Pathol. 2001 Dec;159(6):2107-16.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/11733361/
PMCID PMC1850604

2000

Ontario familial colon cancer registry: methods and first-year response rates.

Authors Cotterchio M, McKeown-Eyssen G, Sutherland H, et al.
Citation Chronic Dis Can. 2000;21(2):81-6.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/11007659/
PMCID NA

1999

Study-design issues in the development of the University of Southern California Consortium’s Colorectal Cancer Family Registry.

Authors Haile RW, Siegmund KD, Gauderman WJ.
Citation J Natl Cancer Inst Monogr. 1999;(26):89-93.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/10854491/
PMCID NA
Combined influence of genetic and dietary factors on colorectal cancer incidence in Japanese Americans.

Authors Le Marchand L.
Citation J Natl Cancer Inst Monogr. 1999;(26):101-5.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/10854493/
PMCID NA
Innovative study designs and analytic approaches to the genetic epidemiology of cancer.

Authors Seminara D, ed.
Citation J Natl Cancer Inst Monogr. 1999;(26):1-105.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/NA/
PMCID NA
Multistage sampling for disease family registries.

Authors Siegmund KD, Whittemore AS, Thomas DC.
Citation J Natl Cancer Inst Monogr. 1999;(26):43-8.
PubMedLink https://pubmed.ncbi.nlm.nih.gov/10854485/
PMCID NA

Click on a year to expand publications for that year.

Associations between pathological features and risk of metachronous colorectal cancer

Improved risk stratification scheme for mismatch repair proficient stage II colorectal cancers using the digital pathology biomarker QuantCRC

Genome-Wide Gene-Environment Interaction Analyses to Understand the Relationship between Red Meat and Processed Meat Intake and Colorectal Cancer Risk

Genotoxic colibactin mutational signature in colorectal cancer is associated with clinicopathological features, specific genomic alterations and better survival

Intratumoral presence of the genotoxic gut bacteria pks+ E. coli, Enterotoxigenic Bacteroides fragilis, and Fusobacterium nucleatum and their association with clinicopathological and molecular features of colorectal cancer

Epidemiologic factors in relation to colorectal cancer risk and survival by genotoxic colibactin mutational signature

The Mutographs biorepository: A unique genomic resource to study cancer around the world

Genome-wide association study and Mendelian randomization analyses provide insights into the causes of early-onset colorectal cancer

Molecular Characteristics of Early-onset Colorectal Cancer According to Detailed Anatomical Locations: Comparison to Later-onset Cases

Validation of a Genetic-Enhanced Risk Prediction Model for Colorectal Cancer in a Large Community-Based Cohort

Elucidating the Risk of Colorectal Cancer for Variants in Hereditary Colorectal Cancer Genes

Using DEPendency of association on the number of Top Hits (DEPTH) as a complementary tool to identify novel colorectal cancer susceptibility loci

A Highly Sensitive Pan-Cancer Test for Microsatellite Instability

The association between genetically elevated polyunsaturated fatty acids and risk of cancer

Probing the diabetes and colorectal cancer relationship using gene – environment interaction analyses

Identifying primary and secondary MLH1 epimutation carriers displaying low-level constitutional MLH1 methylation using droplet digital PCR and genome-wide DNA methylation profiling of colorectal cancers

Identifying metabolic features of colorectal cancer liability using Mendelian randomization

Genome-wide interaction analysis of folate for colorectal cancer risk

Genetically proxied glucose-lowering drug target perturbation and risk of cancer: a Mendelian randomisation analysis

Genetically determined circulating resistin concentrations and risk of colorectal cancer: a two-sample Mendelian randomization study

Elucidating the Risk of Colorectal Cancer for Variants in Hereditary Colorectal Cancer Genes

DNA Mismatch Repair Gene Variant Classification: Evaluating the Utility of Somatic Mutations and Mismatch Repair Deficient Colonic Crypts and Endometrial Glands

Combining Asian-European Genome-Wide Association Studies of Colorectal Cancer Improves Risk Prediction Across Race and Ethnicity

A genetic locus within the FMN1/GREM1 gene region interacts with body mass index in colorectal cancer risk

DNA Methylation Profile in CpG-depleted Regions Uncovers a High-Risk Subtype of Early-stage Colorectal Cancer

T cell-inflamed gene expression profile is associated with favorable disease-specific survival in non-hypermutated microsatellite-stable colorectal cancer patients

A tumor focused approach to resolving the etiology of DNA mismatch repair deficient tumors classified as suspected Lynch syndrome

A tumor focused approach to resolving the etiology of DNA mismatch repair deficient tumors classified as suspected Lynch syndrome

Evaluating Multiple Next-Generation Sequencing–Derived Tumor Features to Accurately Predict DNA Mismatch Repair Status

Prognostic role of detailed colorectal location and tumor molecular features: analyses of 13,101 colorectal cancer patients including 2994 early-onset cases

Separating the effects of early and later life adiposity on colorectal cancer risk: a Mendelian randomization study

Body Mass Index and Molecular Subtypes of Colorectal Cancer

Genetic Predictors for Fecal Propionate and Butyrate-Producing Microbiome Pathway Are Not Associated with Colorectal Cancer Risk: A Mendelian Randomization Analysis

Genome-Wide Analyses Characterize Shared Heritability Among Cancers and Identify Novel Cancer Susceptibility Regions

Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

Genome-wide interaction study with smoking for colorectal cancer risk identifies novel genetic loci related to tumor suppression, inflammation and immune response

Molecular Characteristics of Early-onset Colorectal Cancer According to Detailed Anatomical Locations: Comparison to Later-onset Cases

Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium

Beyond GWAS of Colorectal Cancer: Evidence of Interaction with Alcohol Consumption and Putative Causal Variant for the 10q24.2 Region

Interactions between folate intake and genetic predictors of expression associated with colorectal cancer risk

Genetic regulation of DNA methylation yields novel discoveries in GWAS of colorectal cancer

Body Mass Index, sex, non-steroidal anti-inflammatory drug medications, smoking and alcohol are differentially associated with World Health Organisation criteria and colorectal cancer risk in people with Serrated Polyposis Syndrome: an Australian case-control study

Associations Between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis

Genetically-proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers

Association of germline TYK2 variation with lung cancer and non-Hodgkin lymphoma risk

Genome-Wide Interaction Analysis of Genetic Variants with Menopausal Hormone Therapy for Colorectal Cancer Risk

Large-scale integrated analysis of genetics and metabolomic data reveals potential links between lipids and colorectal cancer risk

Germline MBD4 deficiency causes a multi-tumor predisposition syndrome

Quantitative pathologic analysis of digitized images of colorectal carcinoma improves prediction of recurrence free survival

A validation of models for prediction of mismatch repair gene mutations

Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation

Genome-wide association study identifies tumor anatomical site-specific risk variants for colorectal cancer survival

Beyond GWAS of Colorectal Cancer: Evidence of Interaction with Alcohol Consumption and Putative Causal Variant for the 10q24.2 Region

Diabetes mellitus in relation to colorectal tumor molecular subtypes: A pooled analysis of more than 9000 cases

Identifying colorectal cancer caused by biallelic MUTYH pathogenic variants using tumor mutational signatures

Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals

Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study

Genetic regulation of DNA methylation yields novel discoveries in GWAS of colorectal cancer

Association between germline variants and somatic mutations in colorectal cancer

Risk Stratification for Early-Onset Colorectal Cancer Using a Combination of Genetic and Environmental Risk Scores: An International Multi-Center Study

Cancer Risk C (CR-C), a functional genomics test, is a sensitive and rapid test for germline mismatch repair deficiency

DNA methylation-based signature of CD8+ tumor-infiltrating lymphocytes enables evaluation of immune response and prognosis in colorectal cancer

Dual role of allele-specific DNA hypermethylation within the TERT promoter in cancer

Rare variants in the DNA pathway and the risk of colorectal cancer

Tetranucleotide and Low Microsatellite Instability Are Inversely Associated with the CpG Island Methylator Phenotype in Colorectal Cancer

Salicylic Acid and Risk of Colorectal Cancer: A Two-Sample Mendelian Randomization Study

An integrated mass spectrometry imaging and digital pathology workflow for objective detection of colorectal tumours by unique atomic signatures

Germline and Tumor Sequencing as a Diagnosit Tool to Resolve Suspected Lynch Syndrome

Associations of household income with health-related quality of life following a colorectal cancer diagnosis varies with neighborhood socioeconomic status

Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report

Response to Li and Hopper.

Genetically predicted circulating concentrations of micronutrients and risk of colorectal cancer among individuals of European descent: a Mendelian randomization study

Association Between Smoking and Molecular Subtypes of Colorectal Cancer

A genome-wide search for determinants of survival in 1926 patients with advanced colorectal cancer with follow-up in over 22,000 patients

Genetically predicted physical activity levels are associated with lower colorectal cancer risk: a Mendelian randomisation study

Variation in the Risk of Colorectal Cancer for Lynch Syndrome: A retrospective family cohort study

DNA Methylation Signatures and the Contribution of Age-Associated Methylomic Drift to Carcinogenesis in Early-Onset Colorectal Cancer

Assessment of a Polygenic Risk Score for Colorectal Cancer to Predict Risk of Lynch Syndrome Colorectal Cancer