Our Publications

Click on a year to expand publications for that year.

Alternatively, click the search icon in the top right corner of this page to search for the publication.

2008
  • Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

    Authors Fernandez-Rozadilla C, Timofeeva M, Chen Z. et al
    Citation Nat Genet. 2023 Mar;55(3):519-520.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/36782065/
    PMCID Erratum

  • Genome-wide interaction study with smoking for colorectal cancer risk identifies novel genetic loci related to tumor suppression, inflammation and immune response

    Authors Carreras-Torres R, Kim AE, Lin Y. et al
    Citation Cancer Epidemiol Biomarkers Prev. 2023 Mar 6;32(3):315-328.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/36576985/
    PMCID PMC9992283

  • A validation of models for prediction of mismatch repair gene mutations

    Authors Shyr C, Blackford AL, Huang T. et al
    Citation Genet Med. 2022 Oct;24(10):2155-2166.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/35997715/
    PMCID NIHMID: 1910759

  • Cancer Risk C (CR-C), a functional genomics test, is a sensitive and rapid test for germline mismatch repair deficiency

    Authors Alim I, Loke J, Yam S. et al
    Citation Genet Med. 2022 Sep;24(9):1821-1830.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/35616648/
    PMCID PMC10072225

  • Risk Stratification for Early-Onset Colorectal Cancer Using a Combination of Genetic and Environmental Risk Scores: An International Multi-Center Study

    Authors Archambault AN, Jeon J, Lin Y. et al
    Citation JNCI. 2022 Apr 11;114(4):528-539.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/35026030/
    PMCID PMC9002285

  • Association between germline variants and somatic mutations in colorectal cancer

    Authors Barfield R, Qu C, Steinfelder RS. et al
    Citation Sci Rep. 2022 Jun 17;12(1):10207.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/35715570/
    PMCID PMC9205954

  • Genetic regulation of DNA methylation yields novel discoveries in GWAS of colorectal cancer

    Authors Barfield R, Huyghe JR, Lemire M, et al.
    Citation Cancer Epidemiol Biomarkers Prev. 2022 Mar3;cebp.0724.2021.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/35247911/
    PMCID PMC9081265

  • Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study

    Authors Berstein FM, McCartney DL, Lu AT. et al
    Citation eLife. 2022 Mar 29;11:e75374.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/35346416/
    PMCID PMC9049976

  • Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals

    Authors Chen H, Majumdar A, Wang L, et al.
    Citation HGG Adv. 2021 Jul 8;2(3):100041.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/34355204/
    PMCID PMC8336922

  • Identifying colorectal cancer caused by biallelic MUTYH pathogenic variants using tumor mutational signatures

    Authors Georgeson P, Harrison TA, Pope BJ. et al
    Citation Nat Commun. 2022 Jun 6;13(1):3254.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/35668106/
    PMCID PMC9170691

  • Diabetes mellitus in relation to colorectal tumor molecular subtypes: A pooled analysis of more than 9000 cases

    Authors Harlid S, Van Guelpen B, Qu C. et al
    Citation Int J Cancer. 2022 Aug 1;151(3):348-360.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/35383926/
    PMCID PMC9251811

  • Beyond GWAS of Colorectal Cancer: Evidence of Interaction with Alcohol Consumption and Putative Causal Variant for the 10q24.2 Region

    Authors Jordahl KM, Shcherbina A, Kim AE, et al.
    Citation Cancer Epidemiol Biomarkers Prev. 2022 May 4;31(5):1077-1089.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/35438744/
    PMCID PMC9081195

  • Genome-wide association study identifies tumor anatomical site-specific risk variants for colorectal cancer survival

    Authors Labadie JD, Savas S, Harrison TA. et al
    Citation Sci Rep. 2022 Jan 7;12(1):127.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/34996992/
    PMCID PMC8741984

  • Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation

    Authors Martin S, Tyrrell J, Thomas EL. et al
    Citation Elife. 2022 Jan 25;11:e72452.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/35074047/
    PMCID PMC8789289

  • Associations Between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis

    Authors Murphy N, Song M, Papadimitriou N. et al
    Citation JNCI. 2022 May 9; 114(5): 740-752.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/35048991/
    PMCID PMC9086764

  • Quantitative pathologic analysis of digitized images of colorectal carcinoma improves prediction of recurrence free survival

    Authors Pai RK, Banerjee I, Shivji S. et al
    Citation Gastroenterology. 2022 Aug 16;S0016-5085(22)00951-9.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/35985511/
    PMCID PMC9716432

  • Germline MBD4 deficiency causes a multi-tumor predisposition syndrome

    Authors Palles C, West HD, Chew E, et al.
    Citation Am J Hum Genet. 2022 May 5;109(5):953-960.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/35460607/
    PMCID PMC9118112

  • Large-scale integrated analysis of genetics and metabolomic data reveals potential links between lipids and colorectal cancer risk

    Authors Shu X, Chen Z, Long J, et al.
    Citation Cancer Epidemiol Biomarkers Prev. 2022 Mar 10; cebp.EPI-21-1008-E.2021.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/35266989/
    PMCID PMC9354799

  • Genome-Wide Interaction Analysis of Genetic Variants with Menopausal Hormone Therapy for Colorectal Cancer Risk

    Authors Tian Y, Kim AE, Bien SA. et al
    Citation J Natl Cancer Inst. 2022 Aug 8;114(8):1135-1148.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/35512400/
    PMCID PMC9360460

  • Association of germline TYK2 variation with lung cancer and non-Hodgkin lymphoma risk

    Authors Yarmolinsky J, Amos CI, Hung RJ. et al
    Citation Int J Cancer. 2022 Dec 15;151(12):2155-2160.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/35747941/
    PMCID PMC9588593

  • Genetically-proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers

    Authors Yarmolinsky J, Díez-Obrero V, Richardson TG. et al
    Citation Plos Medicine. 2022 Feb; 19(2): e1003897.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/35113855/
    PMCID PMC8812899

  • Dual role of allele-specific DNA hypermethylation within the TERT promoter in cancer

    Authors Lee DD, Komosa M, Sadhaman S, et al.
    Citation J Clin Invest. 2021 Nov 1;131(21):e146915.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/34720085/
    PMCID PMC8553568

  • Rare variants in the DNA pathway and the risk of colorectal cancer

    Authors Matejcic M, Shaban HA, Quintana MW, et al.
    Citation Cancer Epidemiol Biomarkers Prev. 2021 Feb 24; cebp. 1457.2020.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33627384/
    PMCID PMC8102340

  • Tetranucleotide and Low Microsatellite Instability Are Inversely Associated with the CpG Island Methylator Phenotype in Colorectal Cancer

    Authors Meessen S, Currey N, Jahan Z, et al.
    Citation Cancers. 2021 Jul 14;13(14):3529.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/34298744/
    PMCID PMC8308094

  • Salicylic Acid and Risk of Colorectal Cancer: A Two-Sample Mendelian Randomization Study

    Authors Nounu A, Richmond RC, Stewart ID, et al.
    Citation Nutrients. 2021 Nov 21;13(11):4164.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/34836419/
    PMCID PMC8620763

  • An integrated mass spectrometry imaging and digital pathology workflow for objective detection of colorectal tumours by unique atomic signatures

    Authors Paul B, Kysenius K, Hilton JB, et al.
    Citation Chem Sci. 2021 Jun 29;12(30):10321-10333.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/34476052/
    PMCID PMC8386113

  • Germline and Tumor Sequencing as a Diagnosit Tool to Resolve Suspected Lynch Syndrome

    Authors Pope BJ, Clendenning M, Rosty C, et al.
    Citation J Mol Diagn. 2021 Mar; 23(3):358-371.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33383211/
    PMCID PMC7927277

  • Associations of household income with health-related quality of life following a colorectal cancer diagnosis varies with neighborhood socioeconomic status

    Authors Robinson JRM, Phipps AI, Barrington WE, et al.
    Citation Cancer Epidemiol Biomarkers Prev. 2021 Jul;30(7):1366-1374.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33947657/
    PMCID PMC8254776

  • Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report

    Authors Seppälä TT, Dominguez-Valentin M, Crosbie EJ, et al.
    Citation Eur J Cancer. 2021 May;148:124-133.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33743481/
    PMCID PMC8916840

  • Response to Li and Hopper.

    Authors Thomas M, Sakoda LC, Hoffmeister M, et al.
    Citation Am J Hum Genet. 2021 Mar 4;108(3):527-529.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33667396/
    PMCID PMC8008475

  • Genetically predicted circulating concentrations of micronutrients and risk of colorectal cancer among individuals of European descent: a Mendelian randomization study

    Authors Tsilidis KK, Papadimitriou N, Dimou N, et al.
    Citation Am J Clin Nutr. 2021 Mar 19;nqab003.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33740060/
    PMCID PMC8168352

  • Association Between Smoking and Molecular Subtypes of Colorectal Cancer

    Authors Wang X, Amitay E, Harrison TA, et al.
    Citation JNCI Cancer Spectr. 2021 Jun14;5(4):pkab056.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/34377935/
    PMCID PMC8346704

  • A genome-wide search for determinants of survival in 1926 patients with advanced colorectal cancer with follow-up in over 22,000 patients

    Authors Wills C, He Y, Summers MG, Lin Y, et al.
    Citation Eur J Cancer. 2021 Nov 15;159:247-258.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/34794066/
    PMCID PMC9132154

  • Genetically predicted physical activity levels are associated with lower colorectal cancer risk: a Mendelian randomisation study

    Authors Zhang X, Theodoratou E, Li X, et al.
    Citation Br J Cancer. 2021 Mar;124(7):1330-1338.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33510439/
    PMCID PMC8007642

  • DNA methylation-based signature of CD8+ tumor-infiltrating lymphocytes enables evaluation of immune response and prognosis in colorectal cancer

    Authors Zou Q, Wang X, Ren D. et al
    Citation J Immunother Cancer. 2021 Sep;9(9):e002671.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/34548385/
    PMCID PMC8458312

  • Smoking Behavior and Prognosis After Colorectal Cancer Diagnosis: A Pooled Analysis of 11 Studies

    Authors Alwers E, Carr PR, Banbury B, et al.
    Citation JNCI Cancer Spectr. 2021 Oct 5(5): pkab077.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/34738070/
    PMCID PMC8561259

  • Nongenetic Determinants of Risk for Early-Onset Colorectal Cancer

    Authors Archambault AN, Lin Y, Jeon J, et al.
    Citation JNCI Cancer Spectr. 2021 May 20;5(3):pkab029.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/34041438/
    PMCID PMC8134523

  • Molecular and pathology features of colorectal tumors and patient outcomes are associated with Fusobacterium nucleatum and its subspecies animalis

    Authors Borozan I, Zaidi SH, Harrison TA, et al.
    Citation Cancer Epidemiol Biomarkers Prev. 2021 Nov 4;cebp.EPI-21-0463-A.2021.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/34737207/
    PMCID PMC8755593

  • Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals

    Authors Chen H, Majumdar A, Wang L, et al.
    Citation HGG Adv. 2021 Jul 8;2(3):100041.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/34355204/
    PMCID PMC8336922

  • FamEvent: An R Package for Generating and Modeling Time-to-Event Data in Family Designs

    Authors Choi YH, Briollais L, He W.
    Citation J Stat Softw. 2021 Mar;97(7):10.18637/jss.v097.i07.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/34512212/
    PMCID PMC8427460

  • Two-Sample Mendelian Randomization Analysis of Associations Between Periodontal Disease and Risk of Cancer

    Authors Corlin L, Ruan M, Tsilidis KK, et al.
    Citation JNCI Cancer Spectr. 2021 Apr 19;5(3):pkab037.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/34222791/
    PMCID PMC8242136

  • Lack of an association between gallstone disease and bilirubin levels with risk of colorectal cancer: a Mendelian randomisation analysis

    Authors Culliford R, Cornish AJ, Law PJ, et al.
    Citation Br J Cancer. 2021 Jan 7.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33414539/
    PMCID PMC7961009

  • Circulating levels of testosterone, sex hormone binding globulin and colorectal cancer risk: observational and Mendelian randomization analysis

    Authors Dimou N, Mori N, Harlid S, et al.
    Citation Cancer Epidemiol Biomarkers Prev. 2021 Apr 20;cebp.EPI-20-1690-E.2020.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33879453/
    PMCID PMC8914241

  • Causal effects of lifetime smoking on breast and colorectal cancer risk: Mendelian randomization study

    Authors Dimou N, Yarmolinsky J, Bouras E, et al.
    Citation Cancer Epidemiol Biomarkers Prev. 2021 Mar 2;cebp.EPI-20-1218-E.2020.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33653810/
    PMCID PMC7611442

  • Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report

    Authors Dominguez-Valentin M, Crosbie EJ, Engel C, et al.
    Citation Genet Med. 2021 Apr;23(4):705-712.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33257847/
    PMCID PMC8026395

  • No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in MLH1 and MSH2: A Prospective Lynch Syndrome Database Study

    Authors Dominguez-Valentin M, Plazzer JP, et al.
    Citation J Clin Med. 2021 Jun 28;10(13):2856.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/34203177/
    PMCID PMC8269121

  • Breast Cancer Risk Genes – Association Analysis in More than 113,000 Women

    Authors Dorling L, Carvalho S, Allen J, et al.
    Citation N Engl J Med. 2021 Feb 4;384(5):428-439.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33471991/
    PMCID PMC7611105

  • Evaluating the utility of tumour mutational signatures for identifying hereditary colorectal cancer and polyposis syndrome carriers

    Authors Georgeson P, Pope BJ, Rosty C, et al.
    Citation Gut. 2021 Jan 7. gutjnl-2019-320462.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33414168/
    PMCID PMC8260632

  • Genetically predicted circulating C-reactive protein concentration and colorectal cancer survival: A Mendelian randomization study

    Authors Hua X, Dai JY, Lindström S, et al.
    Citation Cancer Epidemiol Biomarkers Prev. 2021 May 10:cebp.1848.2021.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33972368/
    PMCID PMC8254760

  • Association between post-treatment circulating biomarkers of inflammation and survival among stage II-III colorectal cancer patients

    Authors Hua X, Kratz M, Malen RC, et al.
    Citation Br J Cancer. 2021 Jul 6.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/34230610/
    PMCID PMC8438064

  • Genetic variants associated with circulating C-reactive protein levels and colorectal cancer survival: Sex- and lifestyle factors- specific associations

    Authors Huang Y, Hua X, Labadie JD, et al.
    Citation Int J Cancer. 2021 Dec 9.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/34888857/
    PMCID PMC8897240

  • Genetic architectures of proximal and distal colorectal cancer are partly distinct

    Authors Huyghe JR, Harrison TA, Bien SA, et al.
    Citation Gut 2021 Feb 25;gutjnl-2020-321534.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33632709/
    PMCID PMC8223655

  • Variation in the Risk of Colorectal Cancer for Lynch Syndrome: A retrospective family cohort study

    Authors International Mismatch Repair Consortium.
    Citation Lancet Oncol. 2021 Jul;22(7):1014-1022.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/34111421/
    PMCID PMC8934577

  • Assessment of a Polygenic Risk Score for Colorectal Cancer to Predict Risk of Lynch Syndrome Colorectal Cancer

    Authors Jenkins MA, Buchanan DD, Lai J, et al.
    Citation Cancer Epidemiol Biomarkers Prev. 2021 May;30(5):895-903.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33928216/
    PMCID PMC8062848

  • DNA Methylation Signatures and the Contribution of Age-Associated Methylomic Drift to Carcinogenesis in Early-Onset Colorectal Cancer

    Authors Joo JE, Clendenning M, Wong EM, et al.
    Citation Cancers (Basel) 2021 May 25;13(11):2589.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/34070516/
    PMCID PMC8199056

  • Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study

    Authors Bull CJ, Bell JA, Murphy N, et al.
    Citation BMC Med. 2020 Dec 17;18(1):396.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33327948/
    PMCID PMC7745469

  • Association of Body Mass Index With Colorectal Cancer Risk by Genome-Wide Variants

    Authors Campbell PT, Lin Y, Bien SA, Figueiredo JC, et al.
    Citation JNCI. 2020 Apr 23.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/32324875/
    PMCID PMC7781451

  • Modifiable pathways for colorectal cancer: A mendelian randomisation analysis

    Authors Cornish AJ, Law PJ, Timofeeva M, et al.
    Citation Lancet Gastroenterol Hepatol. 2020 Jan;5(1):55-62.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/31668584/
    PMCID PMC7026696

  • Circulating adipokine concentrations and risk of five obesity-related cancers: A Mendelian randomization study

    Authors Dimou NL, Papadimitriou N, Mariosa D, et al.
    Citation Int J Cancer. 2020 Oct 10.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33038280/
    PMCID PMC7894468

  • A general framework for functionally informed set-based analysis: Application to a large-scale colorectal cancer study

    Authors Dong X, Su YR, Barfield R, et al.
    Citation Plos Genetics. 2020 Aug 24;16(8):e1008947.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/32833970/
    PMCID PMC7470748

  • Monoallelic NTHL1 Loss of Function Variants and Risk of Polyposis and Colorectal Cancer

    Authors Elsayed FA, Grolleman JE, Ragunathan A, et al.
    Citation Gastroenterology. 2020 Aug 26;S0016-5085(20)35113-1.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/32860789/
    PMCID PMC7899696

  • Do the risks of Lynch syndrome-related cancers depend on the parent of origin of the mutation?

    Authors Gemechu SD, van Vliet CM, Win AK, et al.
    Citation Fam Cancer. 2020 Feb 27.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/32107660/
    PMCID PMC7410789

  • Identifying Novel Susceptibility Genes for Colorectal Cancer Risk From a Transcriptome-Wide Association Study of 125,478 Subjects

    Authors Guo X, Lin W, Wen W, Huyghe J, et al.
    Citation Gastroenterology. 2020 Oct 12; S0016-5085(20)35243-4.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33058866/
    PMCID PMC7956223

  • Potential impact of family history-based screening guildelines on the detection of early-onset colorectal cancer

    Authors Gupta S, Bharti B, Ahnen DJ, et al
    Citation Cancer. 2020 Apr 20.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/32307706/
    PMCID PMC7702222

  • Intake of dietary fruit, vegetables, and fiber and risk of colorectal cancer according to molecular subtypes: A pooled analysis

    Authors Hidaka A, Harrison TA, Cao Y, et al.
    Citation Cancer Res. 2020 Aug 14:canres.0168.2020.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/32816852/
    PMCID PMC7572895

  • Limiting oxidative DNA damage reduces microbe-induced colitis-associated colorectal cancer

    Authors Irrazabal T, Thakur BK, Kang M, et al.
    Citation Nat Commun. 2020; 11:1802.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/32286276/
    PMCID PMC7156452

  • Association between known risk factors and colorectal cancer risk in Indigenous people participating in the Ontario Familial Colon Cancer Registry

    Authors Jamal S, Sheppard S, Cotterchio M.
    Citation Curr Oncol. 2020 Aug;27(4):e395-e398.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/32905327/
    PMCID PMC7467780

  • Hemochromatosis risk genotype is not associated with colorectal cancer or age at its diagnosis

    Authors Jarvik GP, Wang X, Fontanillas P, et al.
    Citation HGG Adv. 2020 Aug 25; 1(1):100010.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/35047832/
    PMCID PMC8756515

  • Mendelian Randomization of Circulating Polyunsaturated Fatty Acids and Colorectal Cancer Risk

    Authors Khankari NK, Banbury BL, Borges MC, et al.
    Citation Cancer Epidemiol Biomarkers Prev. 2020 Feb 12.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/32051193/
    PMCID PMC7125012

  • Post-menopausal hormone therapy and colorectal cancer risk by molecularly-defined subtypes and tumor location

    Authors Labadie JD, Harrison TA, Banbury B, et al.
    Citation JNCI Cancer Spectrum. 2020 Oct;4(5).
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/32923935/
    PMCID PMC7477374

  • Identification of Novel Loci and New Risk Variant in Known Loci for Colorectal Cancer Risk in East Asians

    Authors Lu Y, Kweon SS, Cai Q, Tanikawa C, et al.
    Citation Cancer Epidemiol Biomarkers Prev. 2020 Feb;29(2):477-486.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/31826910/
    PMCID PMC7571256

  • Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer

    Authors Montazeri Z, Li X, Nyiraneza C, Ma X, et al.
    Citation Gut. 2020 Aug;69(8).
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/31818908/
    PMCID PMC7398467

  • Circulating Levels of Insulin-like Growth Factor 1 and Insulin-like GrowthFactor Binding Protein 3 Associate With Risk of Colorectal Cancer Based on Serologic and MendelianRandomization Analyses

    Authors Murphy N, Carreras-Torres R, Song M, et al.
    Citation Gastoenterology. 2020 Apr;158(5).
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/31884074/
    PMCID PMC7152801

  • Genetic predictors of circulating 25-hydroxyvitamin D and prognosis after colorectal cancer

    Authors Neumeyer S, Butterbach K, Banbury BL, et al.
    Citation Cancer Epidemiol Biomarkers Prev. 2020Mar 18.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/32188599/
    PMCID PMC7269850

  • Genetic Variants in the Regulatory T cell-Related Pathway and Colorectal Cancer Prognosis

    Authors Neumeyer S, Hua X, Seibold P, et al.
    Citation Cancer Epidemiol Biomarkers Prev. 2020 Dec;29(12):2719-2728.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33008876/
    PMCID PMC7976673

  • A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer

    Authors Nounu A, Greenhough A, Heesom KJ, et al.
    Citation Cancer Epidemiol Biomarkers Prev. 2020 Dec 14;cebp.1176.2020.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33318029/
    PMCID PMC8086774

  • Physical activity and risks of breast and colorectal cancer: A Mendelian randomisation analysis

    Authors Papadimitriou N, Dimou N, Tsilidis KK, et al.
    Citation Nat Commun. 2020 Jan 30;11(1):597.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/32001714/
    PMCID PMC6992637

  • A Latent Unknown Clustering Integrating Multi-Omics Data (LUCID) With Phenotypic Traits

    Authors Peng C, Wang J, Asante I, et al.
    Citation Bioinformatics. 2020 Feb 1;36(3):842-850.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/31504184/
    PMCID PMC7986585

  • Association Between Molecular Subtypes of Colorectal Tumors and Patient Survival, Based on Pooled Analysis of 7 International Studies

    Authors Phipps AI, Alwers E, Harrison T, et al.
    Citation Gastroenterology. 2020 Jun;158(8):2158-2168.e4.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/32088204/
    PMCID PMC7282955

  • The Impact of a Comprehensive Risk Prediction Model for Colorectal Cancer on a Population Screening Program

    Authors Saya S, Emery JD, Dowty JG, et al.
    Citation JNCI Cancer Spectrum. 2020 Oct; 4(5):
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33134836/
    PMCID PMC7583148

  • Circulating Bilirubin Levels and Risk of Colorectal Cancer: Serological and Mendelian Randomization Analyses

    Authors Seyed Khoei N, Jenab M, Murphy N, et al.
    Citation BMC Med. 2020 Sep 3;18(1):229.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/32878631/
    PMCID PMC7469292

  • Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk

    Authors Thomas M, Sakoda LC, Hoffmeister M, et al.
    Citation Am J Hum Genet. 2020 Jul 29:S0002-9297(20)30236-6.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/32758450/
    PMCID PMC7477007

  • Contribution of mRNA Splicing to Mismatch Repair Gene Sequence Variant Interpretation

    Authors Thompson BA, Walters R, Parsons MT, et al.
    Citation Front Genet. 2020; 11:798.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/32849802/
    PMCID PMC7398121

  • Exploratory genome-wide interaction analysis of non-steroidal anti-inflammatory drugs and predicted gene expression on colorectal cancer risk

    Authors Wang X, Su YR, Peterson PS, Bien S,et al
    Citation Cancer Epidemiol Biomarkers Prev. 2020 Jul 10.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/32651213/
    PMCID PMC7556991

  • Functional informed genome-wide interaction analysis of body mass index: diabetes and colorectal cancer risk

    Authors Xia Z, Su YR, Petersen P, et al.
    Citation Cancer Med. 2020 Mar 24.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/32207560/
    PMCID PMC7221445

  • Telomere Maintenance Variants and Survival After Colorectal Cancer: Smoking- And Sex-Specific Associations

    Authors Yin H, Hardikar S, Lindström S, et al.
    Citation Cancer Epidemiol Biomarkers Prev. 2020 Sep;29(9):1817-1824.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/32586834/
    PMCID PMC7928192

  • Landscape of somatic mutations in colorectal cancer and their impact on survival

    Authors Zaidi SH, Harrison TA, Phipps AI, et al.
    Citation Nat Commun. 2020 Jul 20;11(1):3644.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/32686686/
    PMCID PMC7371703

  • Assessment of Polygenic Architecture and Risk Prediction based on Common Variants Across Fourteen Cancers

    Authors Zhang YD, Hurson AN, Zhang H, et al.
    Citation Nat Commun. 2020 Jul 3;11(1):3353.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/32620889/
    PMCID PMC7335068

  • A new comprehensive colorectal cancer risk prediction model incorporating family history, personal characteristics, and environmental factors

    Authors Zheng Y, Hua X, Win AK, et al.
    Citation Cancer Epidemiol Biomarkers Prev. 2020 Mar;29(3):549-557.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/31932410/
    PMCID PMC7060114

  • Height and Colorectal and Endometrial Cancer Risk for Persons with Lynch Syndrome

    Authors Brouwer JGM, Newcomb PA, Bisseling TM, et al.
    Citation Am J Epidemiol. 2020 Aug 17:kwwaa175.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/33524116/
    PMCID PMC8210745

  • Cumulative Burden of Colorectal Cancer-Associated Genetic Variants Is More Strongly Associated With Early-onset vs Late-onset Cancer.

    Authors Archambault AN, Su YR, Jeon J, et al.
    Citation Gastroenterology. 2019 Dec 19.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/31866242/
    PMCID PMC7103489

  • Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer.

    Authors Bien SA, Su YR, Conti DV, et al.
    Citation Hum Genet. 2019 Feb 28.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/30820706/
    PMCID PMC6483948

  • Type 2 diabetes mellitus, blood cholesterol, triglycerideand colorectal cancer risk in Lynch syndrome.

    Authors Dashti SG, Li WY, Buchanan DD, et al.
    Citation Br J Cancer. 2019 Sep 25.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/31551580/
    PMCID PMC6888855

  • Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database.

    Authors Dominguez-Valentin M, Sampson JR, Seppälä TT, et al.
    Citation Genet Med. 2019 Jul 24.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/31337882/
    PMCID PMC7371626

  • Telephone versus in-person colorectal cancer risk and screening intervention for first-degree relatives: A randomized controlled trial.

    Authors Esplen MJ, Harrington S, Leung YW, et al.
    Citation Cancer. 2019 Mar 12.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/30861097/
    PMCID PMC6742581

  • Tumor mutational signatures in sebaceous skin lesions from individuals with Lynch syndrome.

    Authors Georgeson P, Walsh MD, Clendenning M, et al.
    Citation Mol Genet Genomic Med. 2019 Jun 4;e781.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/31162827/
    PMCID PMC6625139

  • Discovery of common and rare genetic risk variants for colorectal cancer.

    Authors Huyghe JR, Bien SA, Harrison TA, et al.
    Citation Nat Genet. 2019 Jan;51(1):76-87.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/30510241/
    PMCID PMC6358437

  • Ability of known susceptibility SNPs to predict colorectal cancer risk for persons with and without a family history.

    Authors Jenkins MA, Win AK, Dowty JG, et al.
    Citation Fam Cancer. 2019 Jun 17.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/31209717/
    PMCID PMC6785388

  • Shared heritability and functional enrichment across six solid cancers.

    Authors Jiang X, Finucane HK, Schumacher FR, et al.
    Citation Nat Commun. 2019 Jan 25;10(1):431.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/30683880/
    PMCID PMC6347624

  • Association analyses identify 31 new risk loci for colorectal cancer susceptibility.

    Authors Law PJ, Timofeeva M, Fernandez-Rozadilla C, et al.
    Citation Nat Commun. 2019 May 14;10(1):2154.
    PubMedLink https://pubmed.ncbi.nlm.nih.gov/31089142/
    PMCID PMC6517433