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Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21
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Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease.
Authors Orlando G, Law PJ, Palin K, et al. Citation Hum Mol Genet. 2016 Jun 1;25(11):2349-2359. PubMedLink https://pubmed.ncbi.nlm.nih.gov/27005424/ PMCID PMC5081051
Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk.
Authors Zeng C, Matsuda K, Jia WG, et al. Citation Gastroenterology. 2016 Jun;150(7):1633-45. PubMedLink https://pubmed.ncbi.nlm.nih.gov/26965516/ PMCID PMC4909543
Common variants in the obesity-associated genes FTO and MC4R are not associated with risk of colorectal cancer.
Authors Yang B, Thrift AP, Figueiredo JC, et al. Citation Cancer Epidemiol. 2016 Oct;44:1-4. PubMedLink https://pubmed.ncbi.nlm.nih.gov/27449576/ PMCID PMC5125024
Association of a let-7 miRNA binding region of TGFBR1 with hereditary mismatch repair proficient colorectal cancer (MSS HNPCC).
Authors Xicola RM, Bontu S, Doyle BJ, et al. Citation Carcinogenesis. 2016 Aug;37(8):751-8. PubMedLink https://pubmed.ncbi.nlm.nih.gov/27234654/ PMCID PMC4967215
Risk of extracolonic cancers for people with biallelic and monoallelic mutations in MUTYH.
Authors Win AK, Reece JC, Dowty JG, et al. Citation Int J Cancer. 2016 Oct 1;139(7):1557-63. PubMedLink https://pubmed.ncbi.nlm.nih.gov/27194394/ PMCID PMC5094810
Prevalence and penetrance of major genes and polygenes for colorectal cancer.
Authors Win AK, Jenkins MA, Dowty JG, et al. Citation Cancer Epidemiol Biomarkers Prev. 2016 Oct 31. PubMedLink https://pubmed.ncbi.nlm.nih.gov/27799157/ PMCID PMC5336409
The Experience of Extended Bowel Resection in Individuals With a High Metachronous Colorectal Cancer Risk: A Qualitative Study.
Authors Steel EJ, Trainer AH, Heriott AG, et al. Citation Oncol Nurs Forum. 2016 Jul 1;43(4):444-52. PubMedLink https://pubmed.ncbi.nlm.nih.gov/27314187/ PMCID PMC5114664
Winner’s Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data.
Authors Shi J, Park JH, Duan J, et al. Citation PLoS Genet. 2016 Dec 30;12(12):e1006493. PubMedLink https://pubmed.ncbi.nlm.nih.gov/28036406/ PMCID PMC5201242