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Prevalence of Alternations in DNA mismatch repair gene alterations in a population-based sample of young-onset colorectal cancer patients.
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The PREMM(1,2,6) model predicts risk of MLH1, MSH2, and MSH6 germline mutations based on cancer history.
Authors Kastrinos F, Steyerberg EW, Mercado R, et al. Citation Gastroenterology. 2011 Jan;140(1):73-81. PubMedLink https://pubmed.ncbi.nlm.nih.gov/20727894/ PMCID PMC3125673
Genotype-environment interactions in microsatellite stable/microsatellite instability-low colorectal cancer: results from a genome-wide association study.
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Development and Validation of an Instrument to Measure the Impact of Genetic Testing on Self-Concept in Lynch Syndrome (LS).
Authors Esplen MJ, Stuckless N, Wong J, et al. Citation Clin Genet. 2011 Nov;80(5):415-23. PubMedLink https://pubmed.ncbi.nlm.nih.gov/21883167/ PMCID PMC3237954
Genetic variation in inflammatory pathways is related to colorectal cancer survival.
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Pre-diagnostic NSAID use but not hormone therapy is associated with improved colorectal cancer survival in women.
Authors Coghill AE, Newcomb PA, Chia VM, et al. Citation Br J Cancer. 2011 Mar 1;104(5):763-8. PubMedLink https://pubmed.ncbi.nlm.nih.gov/21304527/ PMCID PMC3048198
Prediagnostic non-steroidal anti-inflammatory drug use and survival after diagnosis of colorectal cancer.
Authors Coghill AE, Newcomb PA, Campbell PT, et al. Citation Gut. 2011 Apr;60(4):491-8. PubMedLink https://pubmed.ncbi.nlm.nih.gov/21051449/ PMCID PMC3049822
Mutation deep within an intron of MSH2 causes Lynch syndrome.
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Quality Assessment and Correlation of Microsatellite Instability and Immunohistochemical Markers among Population- and Clinic-Based Colorectal Tumors Results from the Colon Cancer Family Registry.
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