Module: colorectal-path

Module Contents

  1. colorectal-malig
    1.CENTER_NO
    2.PERSON_ID
    3.TUMOR_NO
    4.DT_EVAL
    5.BLOCK_SPEC_CID
    6.PROCEDURE_TYPE
    7.MAT_REV_SLIDE
    8.MAT_REV_PATH_RPT
    9.MAT_REV_HOSP_REC
    10.MAT_REV_CA_REGISTRY
    11.MAT_REV_UNK
    12.SPEC_EXAM
    13.PRIM_SITE_CAT
    14.PRIM_HIST_CAT
    15.PRIM_HIST_CAT_OTH_TXT
    16.TUMOR_SIZE
    17.GRADE
    18.MACROSC_TUM_PERF
    19.MARGIN
    20.LC_PERI
    21.LC_CROHN
    22.LC_INFIL
    23.LOC_EXCIS
    24.MARG_INV_DISTAL
    25.MARG_INV_PROXIMAL
    26.MARG_INV_RADIAL
    27.MARG_INV_UNKNOWN
    28.VEN_INV
    29.LYMPHATIC_INV
    30.PERINEURAL_INV
    31.NEOADJ_TRT
    32.NEOADJ_TRT_TYPE
    33.CLINICAL_T
    34.CLINICAL_N
    35.CLINICAL_M
    36.cTNM_STAGE
    37.T_STAGE
    38.LN
    39.LN_POS
    40.LN_EX
    41.DIST_SPREAD
    42.MET_SITE
    43.MET_SITE_BONE
    44.MET_SITE_BRAIN
    45.MET_SITE_LIVER
    46.MET_SITE_LUNG
    47.MET_SITE_NODES
    48.MET_SITE_OVARY
    49.MET_SITE_PERITONEAL
    50.MET_SITE_SMLBWL
    51.MET_SITE_OTHER
    52.MET_SITE_UNKNOWN
    53.MET_SITE_OTH_TXT
    54.MET_SITE_SRC
    55.pTNM_STAGE
    56.SYNCHRON
    57.ADJ_ADEN
    58.ADJ_ADEN_TYPE
    59.ADJ_SIZE
    60.ADJ_GRADE

1CENTER_NOnumber (2,0)Required:true
Center identification number.
Allowable Values
11Sinai Health Systems (formerly Cancer Care Ontario)
12Cedars-Sinai & Cleveland Clinic (formerly USC Consortium)
13University of Melbourne
14University of Hawaii Cancer Center
15Mayo Clinic
16Fred Hutch, Seattle
17UCSF: University of California at San Francisco (formerly CPIC, originally Northern California (NCCC))


2PERSON_IDstring (12)Required:true
Number that uniquely identifies an individual.

3TUMOR_NOnumber (2,0)Required:true
Computer generated sequential number, starting with 1, assigned to each tumor for a given individual when entered into the local system. No adjustment is made when a tumor is deleted from the system. Tumor numbers are never reused. PERSON_NO, TUMOR_NO uniquely identifies each tumor in the CIS. Tumor number should correspond with information from the CANCER file from Volume I.
Allowable Values
1 to 99Range


4DT_EVALstring (8)Required:true
Date specimen evaluated by treating institution (not by CCFR site)
Allowable Values
YYYYMMDD


5BLOCK_SPEC_CIDstring (9)Required:false
Specimen ID number. Consists of concatenation of CENTER_NO (2 digit) + local specimen number (7 characters). References TISSUE file from Volume II Biospecimen Data Dictionary. F-121 : SPECIMEN_ID must begin with CENTER_NO (COLORECT_MALIG) F-200 : SPECIMEN_ID must begin with CENTER_NO (POLYPS)

6PROCEDURE_TYPEnumber (1,0)Required:true
Surgical procedure from which the specimen was obtained.
Allowable Values
1Biopsy
2Resection
3Polypectomy
9Unknown


7MAT_REV_SLIDEnumber (1,0)Required:true
Materials reviewed included slides.
Allowable Values
1Yes
2No
9Unknown


8MAT_REV_PATH_RPTnumber (1,0)Required:true
Materials reviewed included pathology report.
Allowable Values
1Yes
2No
9Unknown


9MAT_REV_HOSP_RECnumber (1,0)Required:true
Materials reviewed included hospital records.
Allowable Values
1Yes
2No
9Unknown


10MAT_REV_CA_REGISTRYnumber (1,0)Required:true
Materials reviewed included cancer registry data.
Allowable Values
1Yes
2No
9Unknown


11MAT_REV_UNKnumber (1,0)Required:true
Materials reviewed unknown.
Allowable Values
1Yes
2No
9Unknown


12SPEC_EXAMnumber (1,0)Required:true
Was specimen examined from primary site or metastatic site?.
Allowable Values
1Primary site
2Metastatic site
3Both
9Unknown


13PRIM_SITE_CATnumber (1,0)Required:true
Primary site of colorectal cancer; Should include hepatic and splenic flexures with transverse colon.
Allowable Values
1Caecum (illeocaecal)
2Ascending (hepatic flexure)
3Transverse (splenic flexure)
4Descending
5Sigmoid
6Rectum (rectosigmoid)
7Appendix
9Unknown/NOS/not reported


14PRIM_HIST_CATnumber (1,0)Required:true
Categorization of histologic type of colorectal primary site; In mucinous carcinomas at least 50% of the tumor comprises areas in which mucin secretion is abundant (more mucus than epithelium). Most poorly differentiated solid types include areas of adenocarcinoma and should not be called undifferentiated. In signet ring cell cancers, 50% of the tumor is composed of signet ring cells.
Allowable Values
1Adenocarcinoma
2Mucinous
3Signet ring
4Undifferentiated (including medullary)
5Other
9Unknown


15PRIM_HIST_CAT_OTH_TXTstring(250)Required:false
Specify primary histologic category text. (Answer if PRIM_HIST_CAT=5)

16TUMOR_SIZE number (3,0)Required:true
Size (mm) of tumor.
Allowable Values
1 to 200Range
0No mass
999Unknown


17GRADEnumber (1,0)Required:true
Grade (worst); The worst area should be graded. Minor fragmentation of glands at the growing tumor margin should be ignored. Well-differentiated cancers have well-formed glands relatively uniform nuclear characteristics. There is a resemblance to adenomatous epithelium. Moderately differentiated cancers have irregular glands but a glandular architecture is still obvious. In poorly differentiated cancers glandular architecture is discerned with difficulty. These are well circumscribed with solid sheets and/or trabeculae and/or cribiforing and/or signet ring areas.
Allowable Values
1Low grade/well differentiated/G1
2Low grade/moderately differentiated/G2
3High grade/poorly differentiated/G3
4Undifferentiated/G4
9Unknown


18MACROSC_TUM_PERF number (1,0)Required:true
Macroscopic tumor perforation. (Do not confuse with microscopic penetration of serosal surface).
Allowable Values
1Present
2Absent
9Unknown


19MARGINnumber (1,0)Required:false
Tumor margin; Cancers considered, as intermediate between expanding and infiltrating should be grouped with the expanding subset. An infiltrating growth pattern may be suspected by naked eye examination of the slide because the pink muscle and blue tumor are merged and difficult to distinguish. Microscopically, infiltrating cancers dissect between muscle bundles, often with a ''raining down'' pattern. There is often diffuse infiltration of fat, perineurial invasion and vascular invasion.
Allowable Values
1Expanding/pushing
2Infiltrating/irregular
9Unknown


20LC_PERInumber (1,0)Required:false
Peritumoral lymphocytes; The presence of peritumoral lymphocytes indicates a distinct inflammatory cuff or cap at the deepest point of penetration of the tumor. The inflammatory cells include neutrophils, eosinophils, macrophages and plasma cells as well as lymphocytes.
Allowable Values
1Yes
2No
9Unknown


21LC_CROHNnumber (1,0)Required:false
Crohn''s-like Lymphocytes; The Crohn''s-like reaction refers to lymphocytes arranged in aggregates or nodules, mainly away from the cancer and in the perirectal or mesenteric fat. It is suggested that at least three lymphoid aggregates should be present in a section.
Allowable Values
1Yes
2No
9Unknown


22LC_INFILnumber (1,0)Required:false
Tumor infiltrating lymphocytes. In marked infiltration, the malignant epithelium is peppered with lymphocytes. The ratio of nuclei (lymphocyte: epithelial) should be at least 1:10 (or at least 12 intraepithelial lymphocytes within a high power (40) field) in the most obviously affected areas (about 3% of cases). Mild infiltration means that the lymphocyte: epithelial ratio should be at least 1:25 (or at least 5 unequivocal intraepithelial lymphocytes within one high power (40) field) in the most obviously affected areas (about 17% of cases). None means a lower frequency or none detected after searching for one minute (about 80% if cases).
Allowable Values
1Yes, marked
2Yes, mild
3No
9Unknown


23LOC_EXCISnumber (1,0)Required:true
Local excision
Allowable Values
1Complete (all margins negative for malignancy)
2Incomplete (one or more margins positive for malignancy)
9Unknown


24MARG_INV_DISTALnumber (1,0)Required:false
Did tumor reach surgical resection distal margin? (Answer if LOC_EXCIS=2)
Allowable Values
1Yes
2No
9Unknown


25MARG_INV_PROXIMALnumber (1,0)Required:false
Did tumor reach surgical resection proximal margin? (Answer if LOC_EXCIS=2)
Allowable Values
1Yes
2No
9Unknown


26MARG_INV_RADIALnumber (1,0)Required:false
Did tumor reach surgical resection radial margin? (Answer if LOC_EXCIS=2)
Allowable Values
1Yes
2No
9Unknown


27MARG_INV_UNKNOWNnumber (1,0)Required:false
Which surgical resection margin(s) involved are unknown? (Answer if LOC_EXCIS=2)
Allowable Values
1Yes
2No
9Unknown


28VEN_INVnumber (1,0)Required:false
Venous invasion (note: formerly called vascular invasion VAS_INV).
Allowable Values
1Yes
2No
9Unknown


29LYMPHATIC_INV number (1,0)Required:false
Lymphatic invasion.
Allowable Values
1Yes
2No
9Unknown


30PERINEURAL_INV number (1,0)Required:false
Perineural invasion.
Allowable Values
1Yes
2No
9Unknown


31NEOADJ_TRTnumber (1,0)Required:true
Neoadjuvant treatment.
Allowable Values
1Yes
2No
9Unknown


32NEOADJ_TRT_TYPEnumber (1,0)Required:false
Neoadjuvant treatment type. (Answer if NEOADJ_TRT=1)
Allowable Values
1Chemotherapy
2Radiation
3Both
9Unknown


33CLINICAL_Tnumber (1,0)Required:false
T stage of colorectal cancer (T of TNM). From treatment data. (Answer if NEOADJ_TRT=1)
Allowable Values
0Tis
1T1
2T2
3T3
4T4
9Unknown


34CLINICAL_Nnumber (1,0)Required:false
Positive nodes? From treatment data. (Answer if NEOADJ_TRT=1)
Allowable Values
1Yes
2No
9Unknown


35CLINICAL_Mnumber (1,0)Required:false
Metastasis? From treatment data. (Answer if NEOADJ_TRT=1)
Allowable Values
1Yes
2No
9Unknown (no definitive statement of distant spread).


36cTNM_STAGEnumber (1,0)Required:false
TNM Stage - Only if reported. Do not derive. From treatment data. (Answer if NEOADJ_TRT=1)
Allowable Values
0In-situ
1I
2II
3III
4IV
9Unknown (if distant spread is unknown)


37T_STAGEnumber (1,0)Required:true
T stage of colorectal cancer (T of TNM). Note: Formerly called T_STAGE_M.
Allowable Values
0Tis
1T1
2T2
3T3
4T4
9Unknown


38LNnumber (1,0)Required:true
Positive nodes?
Allowable Values
1Yes
2No
9Unknown


39LN_POSnumber (2,0)Required:true
Number of positive nodes. Note: codes adopted from SEER & NAACCR standards.
Allowable Values
0 to 99Range
0All nodes examined negative
1-95Number positive
9696 or more positive nodes
97Positive nodes, # of positive nodes not specified
98No nodes examined
99Unknown if nodes are positive or negative; not applicable


40LN_EXnumber (2,0)Required:true
Total number of examined nodes. Note: codes adopted from SEER & NAACCR standards.
Allowable Values
0 to 90, 95, 96, 99Range
0No nodes examined
1 - 89# of nodes examined
9090 or more nodes examined
95No nodes removed
96Nodes examined: # unknown/not stated
99Unknown if nodes examined; not applicable


41DIST_SPREADnumber (1,0)Required:true
Distant spread - colorectal cancer (M in TNM)
Allowable Values
1Yes
2No
9Unknown


42MET_SITEnumber (1,0)Required:false
Metastatic site. Note: Only used for records received before January 20 2020.
Allowable Values
1Liver
2Other
8NA (not applicable)
9Unknown


43MET_SITE_BONEnumber (1,0)Required:false
Metastatic site: Bone? (Answer if DIST_SPREAD=1).
Allowable Values
1Yes
2No
9Unknown


44MET_SITE_BRAINnumber (1,0)Required:false
Metastatic site: Brain/other CNS organ? (Answer if DIST_SPREAD=1).
Allowable Values
1Yes
2No
9Unknown


45MET_SITE_LIVER number (1,0)Required:false
Metastatic site: Liver? (Answer if DIST_SPREAD=1).
Allowable Values
1Yes
2No
9Unknown


46MET_SITE_LUNGnumber (1,0)Required:false
Metastatic site: Lung/other thoracic organ? (Answer if DIST_SPREAD=1).
Allowable Values
1Yes
2No
9Unknown


47MET_SITE_NODES number (1,0)Required:false
Metastatic site: Distant lymph nodes? (Answer if DIST_SPREAD=1).
Allowable Values
1Yes
2No
9Unknown


48MET_SITE_OVARY number (1,0)Required:false
Metastatic site: Ovary/other gynecologic organ? (Answer if DIST_SPREAD=1).
Allowable Values
1Yes
2No
9Unknown


49MET_SITE_PERITONEAL number (1,0)Required:false
Metastatic site: Peritoneal cavity (includes ascites)? (Answer if DIST_SPREAD=1).
Allowable Values
1Yes
2No
9Unknown


50MET_SITE_SMLBWL number (1,0)Required:false
Metastatic site: Small intestine? (Answer if DIST_SPREAD=1).
Allowable Values
1Yes
2No
9Unknown


51MET_SITE_OTHER number (1,0)Required:false
Metastatic site: Other? (Answer if DIST_SPREAD=1).
Allowable Values
1Yes
2No
9Unknown


52MET_SITE_UNKNOWNnumber (1,0)Required:false
Metastatic site: Unknown? (Answer if DIST_SPREAD=1).
Allowable Values
1Yes
2No
9Unknown


53MET_SITE_OTH_TXTstring(80)Required:false
Specify other metastatic site. (Answer if MET_SITE_OTHER =1).

54MET_SITE_SRCnumber (1,0)Required:false
Source of metastatic site report.
Allowable Values
1Pathology Report
2Clinical note
3Operative note
4Radiology report
5Other
9Unknown


55pTNM_STAGEnumber (1,0)Required:true
TNM Stage - Only if reported. Do not derive. Note: Formerly called TNM
Allowable Values
0in-situ lesions
1I
2II
3III
4IV
9Unknown (if DIST_SPREAD scored 9


56SYNCHRONnumber (1,0)Required:true
Synchronous colorectal cancer.
Allowable Values
1Yes
2No
9Unknown


57ADJ_ADENnumber (1,0)Required:false
Contiguous (adjacent) adenoma
Allowable Values
1Yes
2No
9Unknown


58ADJ_ADEN_TYPEnumber (1,0)Required:false
Type of contiguous (adjacent) adenoma (Answer if ADJ_ADEN=1)
Allowable Values
1Tubular adenoma (TA)
2Tubulovillous (TV)
3Villous adenoma (VA)
4Traditional serrated adenoma (TSA)
5Hyperplastic polyp (HP)
6Other (include mixed)
7Adenomatous, type unspecified
8NA (Not applicable) (IF ADJ_ADEN
9Unknown
10Sessile serrated polyp / lesion / adenoma (SSP/L/A)


59ADJ_SIZEnumber (3,0)Required:false
Size (mm) of contiguous (adjacent) adenoma (Answer if ADJ_ADEN=1)
Allowable Values
0 to 990 or 998, 999Range
0No mass (ie. Flat adenoma)
1Microscopic focus/foci
2990
998Not applicable (if ADJ_ADEN
999Unknown (if ADJ_ADEN


60ADJ_GRADEnumber (1,0)Required:false
Grade of contiguous (adjacent) adenoma (Answer if ADJ_ADEN=1)
Allowable Values
1Mild
2Moderate
3Severe/high/in-situ
4No evidence of dysplasia
8Not applicable (if ADJ_ADEN
9Unknown (If ADJ_ADEN