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Category: Publications

Adenomas from individuals with pathogenic biallelic variants in the MUTYH and NTHL1 genes demonstrate base excision repair tumour mutational signature profiles similar to colorectal cancers, expanding potential diagnostic and variant classification applications

Authors Walker R, Joo JE, Mahmood K, et al. Georgeson P.Citation Transl Oncol. 2025 Jan 9PubMed Link https://pubmed.ncbi.nlm.nih.gov/39793275/PMCID PMC11774829

Posted in PublicationsTagged 2025

Body mass index at birth and early life and colorectal cancer: A two-sample Mendelian randomization analysis in European and East Asian genetic similarity populations

Authors Papadimitriou N, Murphy N, Jenab M, et al. and Hughes DJ.Citation Pediatr Obes. 2025 JanPubMed Link https://pubmed.ncbi.nlm.nih.gov/39587448/PMCID PMC11669838

Posted in PublicationsTagged 2025

Characterization of Additive Gene-environment Interactions For Colorectal Cancer Risk

Authors Thomas CE, Lin Y, Kim M, et al. Hsu L.Citation Epidemiology. 2025 Jan 1PubMed Link https://pubmed.ncbi.nlm.nih.gov/39316822/PMCID In process

Posted in PublicationsTagged 2025

Claudin 18.2 Expression in 1,404 Digestive Tract Adenocarcinomas including 1,175 Colorectal Carcinomas: Distinct Colorectal Carcinoma Subtypes are Claudin 18.2 Positive

Authors McHugh KE, Pai RK, Grant RC. Pai RK.Citation Mod Pathol. 2025 Jan 16PubMed Link https://pubmed.ncbi.nlm.nih.gov/39826799/PMCID In process

Posted in PublicationsTagged 2025

Colorectal carcinogenesis in the Lynch syndromes and familial adenomatous polyposis: trigger events and downstream consequences

Authors Møller P, Ahadova A, Kloor M, et al. and Sampson JR.Citation Hered Cancer Clin Pract. 2025 Jan 23PubMed Link https://pubmed.ncbi.nlm.nih.gov/39849512/PMCID PMC11755794

Posted in PublicationsTagged 2025

DNA mismatch repair (MMR) gene mosaicism is rare in people with MMR-deficient cancers

Authors Walker R, Joo JE, Mahmood K, et al. Buchanan DD.Citation Gastroenterology. 2025 Jan 7PubMed Link https://pubmed.ncbi.nlm.nih.gov/39788211/PMCID In process

Posted in PublicationsTagged 2025

Functional variants in the cystic fibrosis transmembrane conductance regulator (CFTR) gene are associated with increased risk of colorectal cancer

Authors Prizment A, Standafer A, Qu C, et al. Pankratz N.Citation Hum Mol Genet. 2025 Jan 1PubMed Link https://pubmed.ncbi.nlm.nih.gov/39825500/

Posted in PublicationsTagged 2025

Menopausal hormone therapy: assessing associations with breast and colorectal cancers by familial risk

Authors MacInnis RJ, Jenkins MA, Milne RL, et al. and Terry MB.Citation JNCI Cancer Spectr. 2025 Jan 3PubMed Link https://pubmed.ncbi.nlm.nih.gov/39673461/PMCID PMC11700558

Posted in PublicationsTagged 2025

Adenomas from individuals with pathogenic biallelic variants in the MUTYH and NTHL1 genes demonstrate base excision repair tumour mutational signature profiles similar to colorectal cancers, expanding potential diagnostic and variant classification applications

Authors Walker R, Joo JE, Mahmood K, et al. and Georgeson P.Citation medRxiv [preprint]. 2024 Aug 9PubMed Link https://pubmed.ncbi.nlm.nih.gov/39148833/PMCID PMC11326331

Posted in PublicationsTagged 2024

Allometric versus traditional body-shape indices and risk of colorectal cancer: a Mendelian randomization analysis

Authors Rontogianni MO, Bouras E, Aglago EK, et al. and Tsilidis KK.Citation Int J Obes (Lond). 2024 MayPubMed Link https://pubmed.ncbi.nlm.nih.gov/38297030/PMCID PMC11058311

Posted in PublicationsTagged 2024

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