Menopausal hormone therapy: assessing associations with breast and colorectal cancers by familial risk

Authors MacInnis RJ, Jenkins MA, Milne RL, et al. and Terry MB.
Citation JNCI Cancer Spectr. 2025 Jan 3
PubMed Link https://pubmed.ncbi.nlm.nih.gov/39673461/
PMCID PMC11700558

Adenomas from individuals with pathogenic biallelic variants in the MUTYH and NTHL1 genes demonstrate base excision repair tumour mutational signature profiles similar to colorectal cancers, expanding potential diagnostic and variant classification applications

Adenomas from individuals with pathogenic biallelic variants in the MUTYH and NTHL1 genes demonstrate base excision repair tumour mutational signature profiles similar to colorectal cancers, expanding potential diagnostic and variant classification applications

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