Summary tables - January 2021

TABLE 1. FAMILY RECRUITMENTa
 
  Male Female Total
       
Population-based Families*     13189
Case probandsb 4317 4420 8737
Affected relativesb 340 382 722
Unaffected relativesc 7401 9950 17351
Spouse Controlsd 363 561 924
Control probandsc 2071   2205  4276
Relatives of controls (Australia only) 310 467 777
 Total population-based individuals 14802  17985  32787 
       
Clinic-based Families**     1860
Affected probandsb 707 649 1356
Unaffected probandsc 130 299 429
Affected relativesb 444 463 908
Unaffected relativesc 3078 3936 7015
Total clinic-based individuals 4359 53477 9708
       
Total Individuals 19165 23333 42500
Total Families     15049
* Includes population-based case proband families from all sites and population-based control proband families from Australia site.
** Includes all clinic-based proband families (counts family ID of affected and unaffected clinic-based probands).
a. Baseline epi data (excluding proxy completion) for females and males
b. Affected with colorectal cancer at baseline interview or biospecimen collection
c. No history of colorectal cancer at baseline interview or biospecimen collection
d. Non blood relation and spouse of case proband recruited to serve as a control.
Note: Blood and non-blood relatives/individuals excluding the probands.

 

TABLE 2. FAMILY DATAa
    Male Female Total
A.Population Based Case Colon Cancer Families      
Probandsb Baseline epi dataa 4317 4420 8737
  1st Follow-up epi data 2642 2976 5618
  2nd Follow-up epi data 1845 2127 3972
  3rd Follow-up epi data 1114 1356 2473
  4th Follow-up epi data 459 607  1072 
  FFQ datae 2093 2407 4500
  Blood/buccal samples 2929 3098 6027 
  Polyp material 17 9 26
  Tumor material 3573 3452 7025
  (CRC tumor material)i 3531 3390 6921
  (Other tumor material)j 101 151 252
  Clinical Dx and Treatment Info 2039 2006 4045
 Relativesc Baseline epi dataa 7741 10332 18073
  1st Follow-up epi data 6014 8299 14313
  2nd Follow-up epi data 4639 6549 11192
  3rd Follow-up epi data 3033 4303 7348
  4th Follow-up epi data 1014 1495 2553
  FFQ datae 3278 4616 7894
  Blood/buccal samples 3826 5491 9317
  Polyp material 9 12 21
  Tumor material 309 383 692
  (CRC tumor material)i 243 260 503
  (Other tumor material)j 79 145 224
  Clinical Dx and Treatment info 50 52 102
Spouse Controlsf Baseline epi dataa 363 561 924
  1st Follow-up epi data 295 484 779
  2nd Follow-up epi data 232 396 629
  3rd Follow-up epi data 169 301 471
  4th Follow-up epi data 69 106 180
  FFQ datae 211 318 529
  Blood/buccal samples 326 510 836
  Polyp material 0 0 0
  Tumor material 4 10 14
  (CRC tumor material)i 1 3 4
  (Other tumor material)j 3 7 10
   Clinical Dx and Treatment info  0  0  0
B.Population Based Control Colon Cancer Families      
Probandsd Baseline epi dataa 2071 2205 4276
  1st Follow-up epi data 668 592 1260
  2nd Follow-up epi data 335 279 614
  3rd Follow-up epi data 0 0 0
  4th Follow-up epi data 0 0 0
  FFQ datae 1151 1025 2176
   Blood/buccal samples 910  759  1669 
  Polyp material      
  Tumor material 0 0 0
  (CRC tumor material)i 0 0 0
  (Other tumor material)j 0 0 0
  Clinical Dx and Treatment Info 0 0 0
 Relativesg Baseline epi dataa 310 467 777
  1st Follow-up epi data 0 0 0
  2nd Follow-up epi data 0 0 0
  3rd Follow-up epi data 0 0 0
  4th Follow-up epi data 0 0 0
  FFQ datae 259 382 641
  Blood/buccal samples 5 5 10
  Polyp material 0 0 0
  Tumor material 0 0 0
  (CRC tumor material)i 0 0 0
  (Other tumor material)j 0 0 0
  Clinical Dx and Treatment info 0 0 0
         
C.Clinic Based Colon Cancer Families*      
Affected Probandsb Baseline epi dataa 707 649 1356
  1st Follow-up epi data 508 501 1009
  2nd Follow-up epi data 369 391 760
  3rd Follow-up epi data 211 222 436
  4th Follow-up epi data 56 66 122
  FFQ datae 236 252 488
  Blood/buccal samples 628 529 1220
  Polyp material 21 23 44
  Tumor material 589 538 1127
  (CRC tumor material)i 580 523 1103
  (Other tumor material)j 77 96 173
  Clinical Dx and Treatment info 359 295 654
 Unaffected Probandsd Baseline epi dataa 130 299 429
  1st Follow-up epi data 122 276 398
  2nd Follow-up epi data 103 230 333
  3rd Follow-up epi data 59 113 173
  4th Follow-up epi data 13 26 39
  FFQ datae 72 183 255
  Blood/buccal samples 111 264 375
  Polyp material 18 34 52
  Tumor material 29 85 114
  (CRC tumor material)i 1 8 9
  (Other tumor material)j 28 81 109
  Clinical Dx and Treatment info 3 3 6
Relativesh Baseline epi dataa 3522 4399 7923
  1st Follow-up epi data 3004 3807 6813
  2nd Follow-up epi data 2380 3088 5470
  3rd Follow-up epi data 1267 1737 3028
  4th Follow-up epi data 231 312 544
  FFQ datae 1921 2564 4486
  Blood/buccal samples 3009 3860 6871
  Polyp material 123 133 256
  Tumor material 481 594 1075
  (CRC tumor material)i 333 365 698
  (Other tumor material)j 172 275 447
  Clinical Dx and Treatment info 15 7 22

 

a. Baseline epi data (excluding proxy completion) for females and males

b. Affected with colorectal cancer at baseline interview or biospecimen collection

c. Affected and unaffected, blood and non-blood, relatives of population based case probands, at baseline interview.

d. No history of colon cancer at baseline interview.

e. Food Frequency Questionnaire

f. Non blood relation and spouse of case proband recruited to serve as a control.

g. Affected and unaffected, blood and non-blood, relatives of population based control probands, at baseline interview.

h. Affected and unaffected, blood and non-blood, relatives of clinic based probands, at baseline interview or biospecimen collection.

i. Individuals diagnosed with colorectal cancer and at least one colorectal tumor specimen obtained.

j. Individuals diagnosed with non-colorectal cancer and at least one tumor specimen obtained. 

* Includes all clinic-based probands and their blood or non-blood relatives
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