Module: colorectal-path

Module Contents

  1. colorectal-malig


1CENTER_NOnumber (2,0)Required:true
Center identification number.
Allowable Values
11Cancer Care Ontario - Colon
12USC Consortium - Colon
13University of Melbourne - Colon
14Cancer Research Center of Hawaii - Colon
15Mayo Clinic - Colon
16Fred Hutchinson, Seattle - Colon
17Northern California (NCCC) Â? Colon


2PERSON_IDstring (12)Required:true
Number that uniquely identifies an individual.

3TUMOR_NOnumber (2,0)Required:true
Computer generated sequential number, starting with 1, assigned to each tumor for a given individual when entered into the local system. No adjustment is made when a tumor is deleted from the system. Tumor numbers are never reused. PERSON_NO, TUMOR_NO uniquely identifies each tumor in the CIS. Tumor number should correspond with information from the CANCER file from Volume I.
Allowable Values
1 to 99Range


4DT_EVALstring (8)Required:true
Date of this record (i.e. date specimen evaluated).

5BLOCK_SPEC_CIDstring (9)Required:false
Specimen ID number. Consists of concatenation of CENTER_NO (2 digit) + local specimen number (7 characters). References TISSUE file from Volume II Biospecimen Data Dictionary. F-121 : SPECIMEN_ID must begin with CENTER_NO (COLORECT_MALIG) F-200 : SPECIMEN_ID must begin with CENTER_NO (POLYPS)

6SPEC_EXAMnumber (1,0)Required:true
Was specimen examined from primary site or metastatic site?.
Allowable Values
1Primary site
2Metastatic site
3Both


7PRIM_SITE_CATnumber (1,0)Required:true
Primary site of colorectal cancer; Should include hepatic and splenic flexures with transverse colon.
Allowable Values
1Caecum
2Asc
3Trans
4Desc
5Sigmoid
6Rectum
7Appendix
9Unknown


8PRIM_HIST_CATnumber (1,0)Required:true
Categorization of histologic type of colorectal primary site; In mucinous carcinomas at least 50% of the tumor comprises areas in which mucin secretion is abundant (more mucus than epithelium). Most poorly differentiated solid types include areas of adenocarcinoma and should not be called undifferentiated. In signet ring cell cancers, 50% of the tumor is composed of signet ring cells.
Allowable Values
1Adenocarcinoma
2Mucinous
3Signet ring
4Undiff
5Other


9GRADEnumber (1,0)Required:true
Grade (worst); The worst area should be graded. Minor fragmentation of glands at the growing tumor margin should be ignored. Well-differentiated cancers have well-formed glands relatively uniform nuclear characteristics. There is a resemblance to adenomatous epithelium. Moderately differentiated cancers have irregular glands but a glandular architecture is still obvious. In poorly differentiated cancers glandular architecture is discerned with difficulty. These are well circumscribed with solid sheets and/or trabeculae and/or cribiforing and/or signet ring areas.
Allowable Values
1Well
2Moderate
3Poor
4Undifferentiated
9Unknown


10MARGINnumber (1,0)Required:false
Tumor margin; Cancers considered, as intermediate between expanding and infiltrating should be grouped with the expanding subset. An infiltrating growth pattern may be suspected by naked eye examination of the slide because the pink muscle and blue tumor are merged and difficult to distinguish. Microscopically, infiltrating cancers dissect between muscle bundles, often with a ''raining down'' pattern. There is often diffuse infiltration of fat, perineurial invasion and vascular invasion.
Allowable Values
1Expanding
2Infiltrating
9Unknown


11LC_PERInumber (1,0)Required:false
Peritumoral lymphocytes; The presence of peritumoral lymphocytes indicates a distinct inflammatory cuff or cap at the deepest point of penetration of the tumor. The inflammatory cells include neutrophils, eosinophils, macrophages and plasma cells as well as lymphocytes.
Allowable Values
1Yes
2No
9Unknown


12LC_CROHNnumber (1,0)Required:false
Crohn''s-like Lymphocytes; The Crohn''s-like reaction refers to lymphocytes arranged in aggregates or nodules, mainly away from the cancer and in the perirectal or mesenteric fat. It is suggested that at least three lymphoid aggregates should be present in a section.
Allowable Values
1Yes
2No
9Unknown


13LC_INFILnumber (1,0)Required:false
Tumor infiltrating lymphocytes. In marked infiltration, the malignant epithelium is peppered with lymphocytes. The ratio of nuclei (lymphocyte:epithelial) should be at least 1:10 (or at least 12 intraepithelial lymphocytes within a high power (40) field) in the most obviously affected areas (about 3% of cases). Mild infiltration means that the lymphocyte: epithelial ratio should be at least 1:25 (or at least 5 unequivocal intraepithelial lymphocytes within one high power (40) field) in the most obviously affected areas (about 17% of cases). None means a lower frequency or none detected after searching for one minute (about 80% if cases).
Allowable Values
1Yes, marked
2Yes, mild
3No
9Unknown


14LOC_EXCISnumber (1,0)Required:true
Local excision
Allowable Values
1Complete
2Incomplete
9Unknown


15TSTAGE_Mnumber (1,0)Required:true
T stage of colorectal cancer
Allowable Values
1 to 4 or 8,9Range
8Tis (Carcinoma in-situ)
9Unknown


16DIST_SPREADnumber (1,0)Required:true
Distant spread - colorectal cancer
Allowable Values
1Yes
2No
9Unknown (score unknown if no definitive statement of distant spread in pathology report)


17LNnumber (1,0)Required:true
Positive nodes?
Allowable Values
1Yes
2No
9Unknown


18LN_POSnumber (2,0)Required:true
Number of positive nodes. Note: codes adopted from SEER & NAACCR standards.
Allowable Values
0 to 99Range
0All nodes examined negative
9696 or more positive nodes
97Positive nodes, number of positive nodes not specified
98No nodes examined
99Unknown if nodes are positive or negative; not applicable


19LN_EXnumber (2,0)Required:true
Total number of examined nodes. Note: codes adopted from SEER & NAACCR standards.
Allowable Values
0 to 89 or 90, 95, 96, 99Range
0No nodes examined
9090 or more nodes examined
95No nodes removed
96Node sampling; number unknown/not stated
99Unknown if nodes examined; not applicable


20VEN_INVnumber (1,0)Required:false
Venous invasion (note: formerly called vascular invasion VAS_INV).
Allowable Values
1Yes
2No
9Unknown


21TNMnumber (1,0)Required:true
TNM Stage
Allowable Values
1I
2II
3III
4IV
0in-situ lesions
9Unknown (if distant spread is scored 9


22SYNCHRONnumber (1,0)Required:true
Synchronous colorectal cancer.
Allowable Values
1Yes
2No
9Unknown


23ADJ_ADENnumber (1,0)Required:false
Contiguous (adjacent) adenoma
Allowable Values
1Yes
2No
9Unknown


24ADJ_ADEN_TYPEnumber (1,0)Required:false
Type of contiguous (adjacent) adenoma
Allowable Values
1TA (tubular adenoma)
2TV (tubulovillous adenoma)
3VA (villous adenoma)
4SA (serrated adenoma)
5HP (hyperplastic polyp)
6Other (include mixed)
7Adenomatous, type unspecified
8NA (Not applicable)
9Unknown


25ADJ_SIZEnumber (3,0)Required:false
Size (mm) of contiguous (adjacent) adenoma
Allowable Values
0 to 990 or 998, 999Range
0No mass
1Microscopic
998Not applicable
999Unknown


26ADJ_GRADEnumber (1,0)Required:false
Grade of contiguous (adjacent) adenoma
Allowable Values
1Mild
2Moderate
3Severe
8Not applicable
9Unknown


27MET_SITEnumber (1,0)Required:false
Metastatic site.
Allowable Values
1Liver
2Other
8NA (not applicable)
9Unknown